Considerations for formulating the second-generation pneumococcal capsular polysaccharide vaccine with emphasis on the cross-reactive types within groups

JB Robbins, R Austrian, CJ Lee, SC Rastogi… - The Journal of infectious …, 1983 - JSTOR
There are several reasons for the resurgence of interest in the prevention of diseases
caused by pneu-mococci. Even when treated with antibiotics, pneumococcal infections …

Pneumococcal vaccines for preventing pneumonia in chronic obstructive pulmonary disease

JAE Walters, JNQ Tang, P Poole… - Cochrane Database …, 2017 - cochranelibrary.com
Background People with chronic obstructive pulmonary disease (COPD) are at increased
risk of pneumococcal disease, especially pneumonia, as well as acute exacerbations with …

Predictors of aspiration pneumonia: how important is dysphagia?

SE Langmore, MS Terpenning, A Schork, Y Chen… - Dysphagia, 1998 - Springer
Aspiration pneumonia is a major cause of morbidity and mortality among the elderly who are
hospitalized or in nursing homes. Multiple risk factors for pneumonia have been identified …

Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease

JAE Walters, S Smith, P Poole… - Cochrane Database …, 2010 - cochranelibrary.com
Background As chronic obstructive pulmonary disease (COPD) progresses, exacerbations
can occur with increasing frequency. One goal of therapy is to prevent these exacerbations …

Clinical efficacy of pneumococcal vaccine in the elderly: a randomized, single-blind population-based trial

I Koivula, M Stén, M Leinonen, PH Mäkelä - The American journal of …, 1997 - Elsevier
PURPOSE: To study the efficacy of pneumococcal capsular polysaccharide vaccine among
the elderly by use of a population-based intervention in one township, Varkaus, Eastern …

Pneumococcal polysaccharide vaccine in young adults and older bronchitics: determination of IgG responses by ELISA and the effect of adsorption of serum with non …

DM Musher, MJ Luchi, DA Watson… - Journal of Infectious …, 1990 - academic.oup.com
Available pneumococcal vaccines provide only limited protection for certain at-risk
populations. Fifteen healthy young adults and 11 older chronic bronchitics received 23 …

Infectious diseases in the elderly

EL Schneider - Annals of Internal Medicine, 1983 - acpjournals.org
As the percent of our population over age 65 increases, infectious disease in this group is
becoming a serious public health concern. Much of our knowledge of infections in the …

Natural and Vaccine-Related Immunity to Streptococcus pneumoniae

DM Musher, AJ Chapman, A Goree… - Journal of Infectious …, 1986 - academic.oup.com
To investigate the protective effects of pneumococcal vaccine, we assayed serum from
healthy adults and from elderly bronchitics for antibody and opsonic activity against nine …

Antibody induction by influenza vaccines in the elderly: a review of the literature

WEP Beyer, AM Palache, M Baljet, N Masurel - Vaccine, 1989 - Elsevier
Conflicting results have been reported concerning the association between high age and
response to influenza vaccines. Some authors have found a reduced response in aged …

Phagocytosis and killing of common bacterial pathogens of the lung by human alveolar macrophages

S Jonsson, DM Musher, A Chapman… - Journal of Infectious …, 1985 - academic.oup.com
To investigate factors that determine susceptibility of the lungs to infection with common
respiratory pathogens, we studied phagocytosis and killing of nontypable Haemophilus …