Emerging role of astrocytes in oxytocin-mediated control of neural circuits and brain functions

A Baudon, EC Creusot, F Althammer, CP Schaaf… - Progress in …, 2022 - Elsevier
The neuropeptide oxytocin has been in the focus of scientists for decades due to its
profound and pleiotropic effects on physiology, activity of neuronal circuits and behaviors …

Oxytocin-based therapies for treatment of Prader-Willi and Schaaf-Yang syndromes: evidence, disappointments, and future research strategies

F Althammer, F Muscatelli, V Grinevich… - Translational …, 2022 - nature.com
The prosocial neuropeptide oxytocin is being developed as a potential treatment for various
neuropsychiatric disorders including autism spectrum disorder (ASD). Early studies using …

Complementary role of oxytocin and vasopressin in cardiovascular regulation

E Szczepanska-Sadowska, A Wsol… - International journal of …, 2021 - mdpi.com
The neurons secreting oxytocin (OXY) and vasopressin (AVP) are located mainly in the
supraoptic, paraventricular, and suprachiasmatic nucleus of the brain. Oxytocinergic and …

Peripartum effects of synthetic oxytocin: The good, the bad, and the unknown

M Rashidi, E Maier, S Dekel, M Sütterlin… - Neuroscience & …, 2022 - Elsevier
The first clinical applications of oxytocin (OT) were in obstetrics as a hormone to start and
speed up labor and to control postpartum hemorrhage. Discoveries in the 1960s and 1970s …

Socio-behavioral dysfunction in disorders of hypothalamic-pituitary involvement: The potential role of disease-induced oxytocin and vasopressin signaling deficits

L Clarke, O Zyga, PL Pineo-Cavanaugh, M Jeng… - Neuroscience & …, 2022 - Elsevier
Disorders involving hypothalamic and pituitary (HPIT) structures—including
craniopharyngioma, Langerhans cell histiocytosis, and intracranial germ cell tumors—can …

[HTML][HTML] Olfactory stimulation inhibits nociceptive signal processing at the input stage of the central trigeminal system

N Papotto, S Reithofer, K Baumert, R Carr, F Möhrlen… - Neuroscience, 2021 - Elsevier
The spinal trigeminal nucleus caudalis (SpVc) in the mammalian brainstem serves a pivotal
function in pain processing. As the main relay center for nociceptive signals, SpVc conducts …

[HTML][HTML] The physiology and pharmacology of oxytocin in labor and in the peripartum period

K Uvnäs-Moberg - American Journal of Obstetrics and Gynecology, 2023 - Elsevier
Oxytocin is a reproductive hormone implicated in the process of parturition and widely used
during labor. Oxytocin is produced within the supraoptic nucleus and paraventricular …

Human endogenous oxytocin and its neural correlates show adaptive responses to social touch based on recent social context

L Handlin, G Novembre, H Lindholm, R Kämpe, E Paul - Elife, 2023 - elifesciences.org
Both oxytocin (OT) and touch are key mediators of social attachment. In rodents, tactile
stimulation elicits the endogenous release of OT, potentially facilitating attachment and other …

Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency

C Atila, J Refardt, M Christ-Crain - Nature Reviews Endocrinology, 2024 - nature.com
Polyuria–polydipsia syndrome can be caused by central diabetes insipidus, nephrogenic
diabetes insipidus or primary polydipsia. To avoid confusion with diabetes mellitus, the …

Whole‐brain mapping of neuronal activity evoked by maternal separation in neonatal mice: An association with ultrasound vocalization

L Mai, H Inada, N Osumi - Neuropsychopharmacology Reports, 2023 - Wiley Online Library
Neonatal mice emit ultrasonic vocalizations (USVs) when separated from their mothers.
Since the USVs attract their mothers' attention and trigger maternal retrieval, they are …