Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors

R Prajapati, SH Seong, SE Park, P Paudel, HA Jung… - Scientific Reports, 2021 - nature.com
Abstract Isoliquiritigenin (= 4, 2′, 4′-Trihydroxychalcone)(ILG) is a major constituent of the
Glycyrrhizae Rhizoma that has significant neuroprotective functions. In the present study, we …

Marine drug discovery through computer-aided approaches

SP Gaudêncio, F Pereira - Marine Drugs, 2023 - mdpi.com
Besides the importance of our oceans as oxygen factories, food providers, shipping
pathways, and tourism enablers, oceans hide an unprecedented wealth of opportunities [1] …

Mechanism of molecular interaction of sitagliptin with human DPP4 enzyme-New Insights

MB Gonzatti, JEM Júnior, AJ Rocha… - Advances in Medical …, 2023 - Elsevier
Abstract Purpose Dipeptidyl peptidase 4 (DPP 4) inactivates a range of bioactive peptides.
The cleavage of insulinotropic peptides and glucagon-like peptide 1 (GLP 1) by DPP 4 …

Antiosteoporosis and bone protective effect of dieckol against glucocorticoid-induced osteoporosis in rats

H Wang, L Yang, J Chao - Frontiers in Endocrinology, 2022 - frontiersin.org
Background Glucocorticoids (GCs) induce osteoporosis, which results in fractures in the
bond, causing significant morbidity. In the conducted study, we examined the …

Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model

H Woo, MK Kim, S Park, SH Han, HC Shin, B Kim… - Marine Drugs, 2021 - mdpi.com
One of the well-known causes of hearing loss is noise. Approximately 31.1% of Americans
between the ages of 20 and 69 years (61.1 million people) have high-frequency hearing …

In Vitro and In Silico Characterization of Kurarinone as a Dopamine D1A Receptor Antagonist and D2L and D4 Receptor Agonist

R Prajapati, SH Seong, P Paudel, SE Park, HA Jung… - ACS …, 2021 - ACS Publications
Alterations in the expression and/or activity of brain G-protein-coupled receptors (GPCRs)
such as dopamine D1R, D2LR, D3R, and D4R, vasopressin V1AR, and serotonin 5-HT1AR …

[PDF][PDF] Research News. Publications, 2020. Volume 4

S Majumdar - 2020 - egrove.olemiss.edu
23. Eissa IH, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, Abdelhady AA, Elhendawy
MA, Radwan MM, ElSohly MA, Mahdy HA. Design, molecular docking, in vitro, and in vivo …