Acute myocardial infarction (AMI) and the heart failure (HF) which may follow are among the
leading causes of death and disability worldwide. As such, new therapeutic interventions are …

Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …

Abstract The Hatter Cardiovascular Institute biennial workshop, originally scheduled for April
2020 but postponed for 2 years due to the Covid pandemic, was organised to debate and …

Impaired function of the endoplasmic reticulum (ER) is followed by evolutionarily conserved
cell stress responses, which are employed by cells, including cardiomyocytes, to maintain …

Mitochondrial dysfunction is a salient feature of myocardial ischemia/reperfusion injury
(MIRI), while the potential mechanism of mitochondrial dynamics disorder remains unclear …

Cardiovascular diseases caused by ischemia are attracting considerable attention owing to
its high morbidity and mortality worldwide. Although numerous agents with cardioprotective …

Using a new-generation drug-eluting stent, we compared the 2-year clinical outcomes of
patients with diabetes mellitus (DM) and non-DM concomitant with a non-ST-segment …

Despite promising breakthroughs in diagnosing and treating acute coronary syndromes,
cardiovascular disease's high global mortality rate remains indisputable. Nearly half of these …

Aims Recovery of blood flow is a therapeutic approach for myocardial infarction but
paradoxically induces injury to the myocardium. Exosomes (exos) are pivotal mediators for …

At present, many patients who undergo reperfusion immediately after percutaneous
coronary intervention will undergo microvascular obstruction and reduction in myocardial …