Disruption of pulmonary vascular homeostasis is a central feature of viral pneumonia,
wherein endothelial cell (EC) death and subsequent angiogenic responses are critical …

Sepsis, a prevalent critical condition in clinics, continues to be the leading cause of death
from infections and a global healthcare issue. Among the organs susceptible to the harmful …

Our understanding of the pathophysiology of pulmonary arterial hypertension (PAH) has
evolved over recent years, with the recognition that endothelial cell (EC) dysfunction and …

Endothelial inflammation is a multifaceted physiological process that plays a pivotal role in
the pathogenesis and progression of diverse diseases, encompassing but not limited to …

Mesenchymal stem cells (MSCs) reside in niches to maintain tissue homeostasis and
contribute to repair and regeneration. Although the physiological functions of blood and …

The human respiratory and circulatory systems collaborate intricately to ensure oxygen
delivery to all cells, which is vital for ATP production and maintaining physiological functions …

Acute lung injury (ALI) is a common complication in patients with severe burns and has a
complex pathogenesis and high morbidity and mortality rates. A variety of drugs have been …

Mammalian lung is the important organ for ventilation and exchange of air and blood. Fresh
air and venous blood are constantly delivered through the airway and vascular tree to the …

Background Acute Respiratory Distress Syndrome (ARDS) is a common condition in the
intensive care unit (ICU) with a high mortality rate, yet the diagnosis rate remains low …

Background: Sepsis is a major cause of ICU admissions, with high mortality and morbidity.
The lungs are particularly vulnerable to infection and injury, and restoration of vascular …