MicroRNA: Potential biomarker and target of therapy in acute lung injury

ZF Jiang, L Zhang, J Shen - Human & experimental …, 2020 - journals.sagepub.com
MicroRNAs (miRNAs) are small noncoding RNAs stretching over 18–22 nucleotides and
considered to be modifiers of many respiratory diseases. They are highly evolutionary …

State-of-the-art review-A review on snake venom-derived antithrombotics: Potential therapeutics for COVID-19-associated thrombosis?

B Kalita, AJ Saviola, SP Samuel… - International Journal of …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent
responsible for the Coronavirus Disease-2019 (COVID-19) pandemic, has infected over 185 …

[HTML][HTML] Secretory Phospholipase A2-IIA Protein and mRNA Pools in Extracellular Vesicles of Bronchoalveolar Lavage Fluid from Patients with Early Acute …

S Papadopoulos, E Kazepidou, MH Antonelou… - Pharmaceuticals, 2020 - mdpi.com
Secretory phospholipase-IIA A2 (sPLA2-IIA) is expressed in a variety of cell types under
inflammatory conditions. Its presence in the bronchoalveolar lavage (BAL) fluid of patients …

Coagulation factor XII regulates inflammatory responses in human lungs

R Hess, L Wujak, C Hesse, K Sewald… - Thrombosis and …, 2017 - thieme-connect.com
Increased procoagulant activity in the alveolar compartment and uncontrolled inflammation
are hallmarks of the acute respiratory distress syndrome (ARDS). Here, we investigated …

GOLDEN anniversary of the acute respiratory distress syndrome: still much work to do!

J Villar, AS Slutsky - Current opinion in critical care, 2017 - journals.lww.com
Because this year is the golden anniversary of the first clinical description of ARDS in 1967,
we have used the acronym 'GOLDEN'to frame our review. It is clear that although much has …

Molecular and immune biomarkers in acute respiratory distress syndrome: a perspective from members of the pulmonary pathology society

VL Capelozzi, TC Allen, MB Beasley… - … of pathology & …, 2017 - meridian.allenpress.com
Acute respiratory distress syndrome (ARDS) is a multifactorial syndrome with high morbidity
and mortality rates, characterized by deficiency in gas exchange and lung mechanics that …

Progranulin improves acute lung injury through regulating the differentiation of regulatory T cells and interleukin‐10 immunomodulation to promote macrophage …

Y Chen, C Wang, K Xie, M Lei, Y Chai… - Mediators of …, 2020 - Wiley Online Library
Progranulin (PGRN), which plays an anti‐inflammatory role in acute lung injury (ALI), is
promising as a potential drug. Studies have shown that regulatory T cells (Tregs) and …

Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide‐Induced ARDS Rat Model

Q Liang, Q Lin, Y Li, W Luo, X Huang… - Journal of …, 2020 - Wiley Online Library
The remodeling of the extracellular matrix (ECM) in the parenchyma plays an important role
in the development of acute respiratory distress syndrome (ARDS), a disease characterized …

[HTML][HTML] Procyanidin B2 Attenuates Sepsis-Induced Acute Lung Injury via Regulating Hippo/Rho/PI3K/NF-κB Signaling Pathway

GO Kim, DH Park, JS Bae - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute lung injury (ALI) is a frequent and challenging aspect of sepsis that currently lacks
effective treatments. Procyanidin B2 (PB2) has anti-inflammatory and antioxidant properties …

[PDF][PDF] Acute respiratory distress syndrome

A Bakhtiar, RA Maranatha - Jurnal Respirasi, 2018 - e-journal.unair.ac.id
Acute respiratory distress syndrome (ARDS) is a syndrome, a combination of clinical and
physiological observations that describe a pathological state. The pathogenesis of ARDS is …