Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Background: The detrimental impact of fluid overload (FO) on intensive care unit (ICU)
morbidity and mortality is well known. However, research to identify subgroups of patients …

Monitoring regional blood flow distribution in the lungs appears to be useful for individually
optimizing ventilation therapy. Electrical impedance tomography (EIT) can be used at the …

Background Internal redistribution of gas, referred to as pendelluft, is a new potential
mechanism of effort-dependent lung injury. Neurally-adjusted ventilatory assist (NAVA) and …

Human microbiota produces metabolites that may enter the bloodstream and exert systemic
influence on various functions including mitochondrial. Mitochondria are not only a target for …

Background Sodium bicarbonate (SB) infusion is commonly used to correct metabolic
acidosis, but its clinical efficacy remains controversial. This study aims to investigate whether …

Abstract Introduction: The Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100) is a
hemoperfusion device that can remove pathogens from central circulation. However, the …

Background. Acute kidney injury (AKI) is a major medical problem affecting patients' quality
of life and healthcare costs. Objectives. This study evaluated the severity, risk factors, and …

Sepsis is a life-threatening organ dysfunction caused by the host's uncontrolled response to
infection, impacting millions of people around the world and killing between one in three and …

Objective: This study aimed to explore the effectiveness of sodium bicarbonate (SB) infusion
on mortality in elderly septic patients with acute metabolic acidosis (MA) and in other …