With the rapid development of nanotechnology in the recent decade, novel DNA and RNA
delivery systems for gene therapy have become available that can be used instead of viral …

Introduction: Delivery of nucleic acid-based molecules in human cells is a highly studied
approach for the treatment of several disorders including monogenic diseases and cancers …

Molecular targeting of nanoparticle drug carriers promises maximized therapeutic impact to
sites of disease or injury with minimized systemic effects. Precise targeting demands …

Vaccines have shown great success in treating and preventing tumors and infections, while
adjuvants are always demanded to ensure potent immune responses. Polyethylenimine …

Gene delivery systems necessitate the gene therapy, which is a unique approach for
applying the tunable genes to treat any diseases. To tackle down the disadvantages of viral …

In this study, a pH sensitive chimeric peptide is developed to codeliver a photosensitizer,
protoporphyrin IX (PpIX), and plasmid DNA simultaneously. In the presence of matrix …

Humoral and cellular host defense mechanisms including diverse phagocytes, leukocytes,
and immune cells have evolved over millions of years to protect the body from microbes and …

A promising approach for addressing a range of diseases lies in the delivery of functional
biomacromolecules such as nucleic acids or proteins to cells. Polymers, peptides and the …

The emerging field of bionanotechnology aims at advancing colloidal and biomedical
research via introduction of multifunctional nanoparticle-based containers intended for both …

In this study, a modified dehydropeptide, Boc–FΔF–εAhx–OH, was conjugated with an
aminoglycoside antibiotic, neomycin, to construct a multifunctional conjugate, Pep–Neo. The …