The regenerative medicine field is large, diverse and active worldwide. A variety of different
organizational and product models have been successful, and pioneering entrepreneurs …

Oocyte and embryo donation have evolved significantly since they were first introduced to
treat human infertility nearly four decades ago. Social, ethical, and regulatory challenges to …

Input from various signaling pathways in conjunction with specific transcription factors (TFs),
noncoding RNAs, and epigenetic modifiers governs the maintenance of cellular identity …

Pluripotent cells arise within the inner cell mass (ICM) of mammals and have the potential to
generate all cell types of the adult organism through a process of commitment and ordered …

Health problems are rising worldwide, be it as a consequence of lifestyle and longevity in
increasingly affluent societies or due to a sharp rise in bacterial antibiotic resistance. The …

Stem cells have generated great interest for their potential therapeutic use because of their
capacity to self-renew indefinitely and to generate all cell lineages (pluripotency). Many …

Financial compensation of women donating oocytes for reproductive or research purposes
is justified on ethical grounds and should acknowledge the time, inconvenience, and …

According to NK Jerne the somatic generation of immune recognition occurs in conjunction
with germ cell evolution and precedes the formation of the zygote, ie operates before clonal …

The oocyte, a long-lived, post-mitotic cell, is the locus of reproductive aging in women.
Female germ cells replicate only during fetal life and age throughout reproductive life …

Stem cells divide by asymmetric division and display different degrees of potency, or ability
to differentiate into various specialized cell types. Owing to their unique regenerative …