In brief Epigenetic reprogramming after mammalian somatic cell nuclear transfer is often
incomplete, resulting in low efficiency of cloning. However, gene expression and histone …

Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can provide
sources for midbrain dopaminergic (mDA) neural progenitors (NPCs) for cell therapy to treat …

In recent years, the cloning technology has remarkably developed in Iran, but unfortunately,
the required legal framework has not been created to support and protect such …

Inherent and acquired defects in gene expression, protein homeostasis, metabolic
pathways, and organelle function are linked to aging and a wide range of human diseases …

Clear cause-and-effect relationships are commonly established between genotype and the
inherited risk of acquiring human and plant diseases and aberrant phenotypes. By contrast …

After the development of induced pluripotent stem cells (IPSCs) in 2007, the pressure to
commercialize women's eggs for stem cell research could have been expected to lessen …

Induced pluripotent stem cells (iPSCs) hold much promise in the quest for personalised cell
therapies. However, the persistence of founder cell mitochondrial DNA (mtDNA) mutations …

The future hope of generated induced pluripotent stem cells (iPS cells) from Alzheimer's
disease patients is multifold. Firstly, they may help to uncover novel mechanisms of the …

Biologically versatile basic fibroblast growth factor (bFGF), well known for roles of signaling
molecules between cells and regulating various cellular processes, has been proven to …

Using of embryonic stem cells (ESCs) could improve production traits and disease
resistance by improving the efficiency of somatic cell nuclear transfer (SCNT) technology …