Platelets are a heterogeneous small anucleate blood cell population with a central role both
in physiological haemostasis and in pathological states, spanning from thrombosis to …

Background: Epilepsy is the second most common disease caused by multiple factors and
characterized by an excessive discharge of certain neurons in the nervous system …

Background: Recently, the European Food Safety Authority approved a claim concerning the
benefits of olive oil polyphenols for the protection of LDL from oxidation. Polyphenols could …

NLRP3 inflammasome not only functions as a critical effector in innate immunity, but also
triggers the production of proinflammatory cytokines involved in inflammation-associated …

An increasing body of evidence indicates that inflammation and apoptosis are involved in
the development of acute myocardial infarction (AMI). In this study, we sought to investigate …

The CD40–CD40 ligand (CD40L) dyad represents a scientific and clinical field that has
raised many controversies in the past and cannot be clearly defined as being an either …

Despite years of encouraging translational research, ischemic stroke still remains as one of
the highest unmet medical needs nowadays, causing a tremendous burden to health care …

Platelets primarily mediate hemostasis and thrombosis, whereas leukocytes are responsible
for immune responses. Since platelets interact with leukocytes at the site of vascular injury …

Background: Pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease due
to the lack of specific early diagnostic markers. To improve the outcomes, proteomic …

Upon activation, platelets release a plethora of factors which help to mediate their dynamic
functions in hemostasis, inflammation, wound healing, tumor metastasis and angiogenesis …