According to the 2020 global cancer data released by the World Cancer Research Fund
(WCRF) International, gastric cancer (GC) is the fifth most common cancer worldwide, with …

The CBL (Casitas B-lineage lymphoma) family, as a class of ubiquitin ligases, can regulate
signal transduction and activate receptor tyrosine kinases through various tyrosine kinase …

Abstract A Kinase Interacting Protein 1 (AKIP1) is found to be overexpressed in a variety of
human cancers and associated with patients' worse prognosis. Several studies have …

Abstract Glioblastoma, IDH-Wild type (GBM, CNS WHO Grade 4) is a highly heterogeneous
and aggressive primary malignant brain tumor with high morbidity, high mortality, and poor …

Background The E3 ubiquitin ligase HECTD3 is a homologue of the E6-related protein
carboxyl terminus, which plays a crucial role in biological processes and tumourigenesis …

GC (Gastric cancer) is one of the most common malignant tumours, with over 95% of gastric
cancer patients being adenocarcinoma and most gastric cancer patients having no apparent …

The process of ubiquitination regulates the degradation, transport, interaction, and
stabilization of substrate proteins, and is crucial for cell signal transduction and function. TNF …

Background Nonstructural maintenance of chromatin condensin I complex subunit G
(NCAPG), also known as non-structural maintenance of chromosomes condensin I complex …

Patients diagnosed with brain glioma have a poor prognosis and limited therapeutic options.
LGR4 is overexpressed in brain glioma and involved in the tumorigenesis of many tumors …

Background The development of cancer is accompanied by metabolic reprogramming, and
the liver serves as a central hub for lipid transportation. Apigenin, a plant-derived flavonoid …