[HTML][HTML] Correlates of adjuvanticity: A review on adjuvants in licensed vaccines
G Del Giudice, R Rappuoli, AM Didierlaurent - Seminars in immunology, 2018 - Elsevier
After decades of slow progress, the last years have seen a rapid acceleration of the
development of adjuvanted vaccines which have lately been approved for human use …
development of adjuvanted vaccines which have lately been approved for human use …
Mechanisms underlying T cell ageing
JJ Goronzy, CM Weyand - Nature Reviews Immunology, 2019 - nature.com
T cell ageing has a pivotal role in rendering older individuals vulnerable to infections and
cancer and in impairing the response to vaccination. Easy accessibility to peripheral human …
cancer and in impairing the response to vaccination. Easy accessibility to peripheral human …
Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …
[PDF][PDF] Aging and the immune system: the impact of immunosenescence on viral infection, immunity and vaccine immunogenicity
CX Chan, YO Yang, GHM Cheng, SK Gera… - Immune …, 2019 - synapse.koreamed.org
Background Prophylactic pinning of the uninvolved side after unilateral slipped capital
femoral epiphysis (SCFE) is controversial. The alpha angle, a measurement of femoral head …
femoral epiphysis (SCFE) is controversial. The alpha angle, a measurement of femoral head …
The immune system and its dysregulation with aging
L Müller, S Di Benedetto, G Pawelec - … and cell biology of ageing: Part II …, 2019 - Springer
Aging leads to numerous changes that affect all physiological systems of the body including
the immune system, causing greater susceptibility to infectious disease and contributing to …
the immune system, causing greater susceptibility to infectious disease and contributing to …
Dynamics of population immunity due to the herd effect in the COVID-19 pandemic
VJ Clemente-Suárez, A Hormeño-Holgado, M Jiménez… - Vaccines, 2020 - mdpi.com
The novel Coronavirus 2 Severe Acute Respiratory Syndrome (SARS-Cov-2) has led to the
Coronavirus Disease 2019 (COVID-19) pandemic, which has surprised health authorities …
Coronavirus Disease 2019 (COVID-19) pandemic, which has surprised health authorities …
Age related human T cell subset evolution and senescence
M Li, D Yao, X Zeng, D Kasakovski, Y Zhang, S Chen… - Immunity & …, 2019 - Springer
T cells are fundamental effector cells against viruses and cancers that can be divided into
different subsets based on their long-term immune protection and immediate immune …
different subsets based on their long-term immune protection and immediate immune …
Immunosenescence: A systems-level overview of immune cell biology and strategies for improving vaccine responses
SN Crooke, IG Ovsyannikova, GA Poland… - Experimental …, 2019 - Elsevier
Immunosenescence contributes to a decreased capacity of the immune system to respond
effectively to infections or vaccines in the elderly. The full extent of the biological changes …
effectively to infections or vaccines in the elderly. The full extent of the biological changes …
Human B-1 cells and B-1 cell antibodies change with advancing age
N Rodriguez-Zhurbenko, TD Quach… - Frontiers in …, 2019 - frontiersin.org
Age-related deficits in the immune system have been associated with an increased
incidence of infections, autoimmune diseases, and cancer. Human B cell populations …
incidence of infections, autoimmune diseases, and cancer. Human B cell populations …
Vaccination as a preventative measure contributing to immune fitness
B Laupèze, G Del Giudice, MT Doherty, R Van der Most - npj Vaccines, 2021 - nature.com
The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect
consequences may include maintenance of homeostasis through prevention of infection …
consequences may include maintenance of homeostasis through prevention of infection …