Placental Exosomes as Biomarkers for Maternal Diseases: Current Advances in Isolation, Characterization, and Detection
Serving as the interface between fetal and maternal circulation, the placenta plays a critical
role in fetal growth and development. Placental exosomes are small membrane-bound …
role in fetal growth and development. Placental exosomes are small membrane-bound …
Circulating extracellular vesicles in healthy and pathological pregnancies: A scoping review of methodology, rigour and results
MVC Barnes, P Pantazi, B Holder - Journal of Extracellular …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) play a crucial role in pregnancy, revealed by the presence of
placental‐derived EVs in maternal blood, their in vitro functionality, and their altered cargo in …
placental‐derived EVs in maternal blood, their in vitro functionality, and their altered cargo in …
Placenta-derived microRNAs in the pathophysiology of human pregnancy
P Xu, Y Ma, H Wu, YL Wang - Frontiers in cell and developmental …, 2021 - frontiersin.org
In placental mammals, reproductive success, and maternal-fetal health substantially depend
on a well-being placenta, the interface between the fetus and the mother. Disorders in …
on a well-being placenta, the interface between the fetus and the mother. Disorders in …
Role of microRNAs in trophoblast invasion and spiral artery remodeling: implications for preeclampsia
H Hayder, Y Shan, Y Chen, JA O'Brien… - Frontiers in Cell and …, 2022 - frontiersin.org
It is now well-established that microRNAs (miRNAs) are important regulators of gene
expression. The role of miRNAs in placental development and trophoblast function is …
expression. The role of miRNAs in placental development and trophoblast function is …
Endometrial small extracellular vesicles regulate human trophectodermal cell invasion by reprogramming the phosphoproteome landscape
A series of cyclical events within the uterus are crucial for pregnancy establishment. These
include endometrial regeneration following menses, under the influence of estrogen …
include endometrial regeneration following menses, under the influence of estrogen …
Diagnostic biomolecules and combination therapy for pre-eclampsia
Abstract Pre-eclampsia (PE), associated with placental malperfusion, is the primary reason
for maternal and perinatal mortality and morbidity that can cause vascular endothelial injury …
for maternal and perinatal mortality and morbidity that can cause vascular endothelial injury …
The role of non-coding RNAs in the human placenta
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs,
and species, which has been broadly recognized since the human ENCODE project and …
and species, which has been broadly recognized since the human ENCODE project and …
Circulating miRNAs and preeclampsia: from implantation to epigenetics
SR Giannubilo, M Cecati, D Marzioni… - International Journal of …, 2024 - mdpi.com
In this review, we comprehensively present the literature on circulating microRNAs
(miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the …
(miRNAs) associated with preeclampsia, a pregnancy-specific disease considered the …
Regulatory roles of non-coding RNAs and m6A modification in trophoblast functions and the occurrence of its related adverse pregnancy outcomes
W Rong, W Shukun, W Xiaoqing, H Wenxin… - Critical Reviews in …, 2022 - Taylor & Francis
Adverse pregnancy outcomes, such as preeclampsia, gestational diabetes mellitus, fetal
growth restriction, and recurrent miscarriage, occur frequently in pregnant women and might …
growth restriction, and recurrent miscarriage, occur frequently in pregnant women and might …
Integrative analysis of circulating microRNAs and the placental transcriptome in recurrent pregnancy loss
N Xu, X Zhou, W Shi, M Ye, X Cao, S Chen… - Frontiers in …, 2022 - frontiersin.org
Recurrent pregnancy loss (RPL) is a major type of pathological pregnancy that still lacks
reliable early diagnosis and effective treatment. The placenta is critical to fetal development …
reliable early diagnosis and effective treatment. The placenta is critical to fetal development …