Emerging patterns of regulatory T cell function in tuberculosis

A Ahmed, A Vyakarnam - Clinical & Experimental Immunology, 2020 - academic.oup.com
Tuberculosis (TB) is one of the top 10 causes of mortality worldwide from a single infectious
agent and has significant implications for global health. A major hurdle in the development …

IL-4 subverts mycobacterial containment in Mycobacterium tuberculosis-infected human macrophages

A Pooran, M Davids, A Nel, A Shoko… - European …, 2019 - Eur Respiratory Soc
Protective immunity against Mycobacterium tuberculosis is poorly understood. The role of
interleukin (IL)-4, the archetypal T-helper type 2 (Th2) cytokine, in the immunopathogenesis …

[HTML][HTML] Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional …

MA Vickers, F Darboe, CN Muefong, G Mbayo… - Frontiers in …, 2020 - frontiersin.org
Background Blood-based biomarkers have been proposed as an alternative to current
sputum-based treatment monitoring methods in active tuberculosis (ATB). The aim of this …

[HTML][HTML] Intra-abdominal infection in acute pancreatitis in eastern China: microbiological features and a prediction model

C Zhu, S Zhang, H Zhong, Z Gu, Y Kang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background This study aimed to investigate the microbiol distribution of intra-abdominal
infection in patients with acute pancreatitis, and to develop a reliable prediction model to …

[HTML][HTML] CD38 expression by antigen-specific CD4 T cells is significantly restored 5 months after treatment initiation independently of sputum bacterial load at the time …

H Hiza, J Hella, A Arbués, M Sasamalo… - Frontiers in …, 2022 - frontiersin.org
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising
candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb) …

[HTML][HTML] Frequency of CD4+ regulatory T cells and modulation of CD4+ T lymphocyte activation in pleural tuberculoma

W Gao, N Yang, S Ji, Y Zeng - Tuberculosis, 2022 - Elsevier
Background The expression of regulatory T cells (Tregs) is elevated in patients with active
tuberculosis (TB) or multidrug-resistant TB. However, it remains uncertain whether Tregs …

Lymphopenia and high Ki-67 expression in peripheral blood CD4+ and CD8+ T cells associate with progressive sarcoidosis

S Kullberg, J Grunewald… - BMJ Open Respiratory …, 2023 - bmjopenrespres.bmj.com
Background Early identification of patients at risk for progressive sarcoidosis may improve
intervention. High bronchoalveolar lavage fluid (BALF) lymphocytes and peripheral blood …

结核性胸膜炎患者外周血和胸水中Thl7, Thl 细胞检测分析.

张洁云, 廖明凤, 韦彩岭, 陈为鑫… - China Tropical …, 2020 - search.ebscohost.com
目的探讨结核性胸膜炎患者Th17, Th1 细胞免疫应答的特性及作用. 方法应用流式细胞术检测30
例健康对照组(HD), 23 例潜伏感染组(LTBI), 20 例结核性胸膜炎组(TP) 患者外周血单个核细胞 …

CD38 expression by antigen-specific CD4 T cells correlates with sputum bacterial load at time of tuberculosis diagnosis and is significantly restored 5-months after …

H Hiza, J Hella, A Arbués, M Sasamalo, V Misana… - medRxiv, 2022 - medrxiv.org
ABSTRACT T cell activation markers (TAM) expressed by antigen-specific T cells constitute
promising candidates to attest the presence of an active infection by Mycobacterium …

Cellular immune ontogeny and birth transcriptome in HIV-exposed uninfected infants

A Kiravu - 2021 - open.uct.ac.za
Background. In some regions of Sub-Saharan Africa, up to 30% of newborns are born to
mothers infected with human immunodeficiency virus (HIV). Maternal antiretroviral treatment …