Background Fungal infections of the central nervous system (FIs-CNS) have become
significantly more common over the past 2 decades. Invasion of the CNS largely depends on …

Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Human fungal diseases differ fundamentally from other infections in diverse ways. As
eukaryotic pathogens, fungi share many similarities with their host cells, which impairs the …

Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …

The possibility that patients diagnosed with Alzheimer's disease (AD) have disseminated
fungal infection has been recently advanced by the demonstration of fungal proteins and …

Cryptococcus neoformans is the most lethal pathogen of the central nervous system. The
gold standard treatment of cryptococcosis, a combination of amphotericin B with 5 …

Background: Recommendations for managing patients with cerebral cryptococcomas are
scarce across multiple clinical guidelines. Due to the deficiency of high-quality data coupled …

Cryptococcus neoformans causes lethal meningitis and accounts for approximately 10%–
15% of AIDS-associated deaths worldwide. There are major gaps in our understanding of …

It is estimated that fungal infections cause 1 million deaths annually, accounting for 50% of
all AIDS-related deaths [1]. In this specific patient group, data from 2009 revealed that fungal …

Background: Cryptococcus neoformans is an opportunistic fungal pathogen that causes
infections mainly in immunosuppressed individuals, such as transplant recipients. Aims: This …