Impact of TRPV1 on Pathogenesis and Therapy of Neurodegenerative Diseases
W Wang, T Sun - Molecules, 2023 - mdpi.com
Transient receptor potential vanilloid 1 (TRPV1) is a transmembrane and non-selective
cation channel protein, which can be activated by various physical and chemical stimuli …
cation channel protein, which can be activated by various physical and chemical stimuli …
N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes
J Joffre, E Wong, S Lawton, E Lloyd, N Nguyen… - Journal of …, 2022 - Springer
Background The transient receptor potential vanilloid 1 (TRPV1) participates in
thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain …
thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain …
TRPV1 Channel activated by the PGE2/EP4 pathway mediates spinal hypersensitivity in a mouse model of vertebral endplate degeneration
S Liu, Q Wang, Z Li, L Ma, T Li, Y Li… - Oxidative Medicine …, 2021 - Wiley Online Library
Low back pain (LBP) is the primary cause of disability globally. There is a close relationship
between Modic changes or endplate defects and LBP. Endplates undergo ossification and …
between Modic changes or endplate defects and LBP. Endplates undergo ossification and …
Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn
Background Opioid analgesics remain widely used for pain treatment despite the related
serious side effects. Some of those, such as opioid tolerance and opioid-induced …
serious side effects. Some of those, such as opioid tolerance and opioid-induced …
[HTML][HTML] Dual effect of anandamide on spinal nociceptive transmission in control and inflammatory conditions
M Pontearso, J Slepicka, A Bhattacharyya… - Biomedicine & …, 2024 - Elsevier
Anandamide (AEA) is an important modulator of nociception in the spinal dorsal horn, acting
presynaptically through Cannabinoid (CB 1) and Transient receptor potential vanilloid …
presynaptically through Cannabinoid (CB 1) and Transient receptor potential vanilloid …
Inhibition of synaptic transmission by anandamide precursor 20: 4-NAPE is mediated by TRPV1 receptors under inflammatory conditions
D Spicarova, V Nerandzic, D Muzik… - Frontiers in Molecular …, 2023 - frontiersin.org
Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel,
and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in …
and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in …