Context Continuing advances in genotyping technologies and the inclusion of DNA
collection in observational studies have resulted in an increasing number of genetic …

Gastric cancer is in decline in most developed countries; however, it still accounts for a
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …

Background Polymorphisms in DNA repair genes have been associated to repair DNA
lesions, and might contribute to the individual susceptibility to develop different types of …

Purpose Cisplatin kills tumor cells through DNA cross linking. Alterations in the function of
DNA repair genes may affect DNA repair proficiency and influence cancer patients' …

The X-ray repair cross-complementing group 3 (XRCC3) is a highly suspected candidate
gene for cancer susceptibility. However, association studies on the XRCC3 polymorphisms …

Background: Genetic polymorphisms in DNA repair genes may influence individual variation
in DNA repair capacity, which may be associated with a higher risk of developing cancer …

The purpose of this report is to review the relationship between genetic polymorphisms
involved in carcinogen metabolism, alcohol metabolism and cell-cycle control with the risk of …

The aim of this report is to review and evaluate, in a comprehensive manner, the published
data regarding the contribution of genetic polymorphisms to risk of head and neck cancer …

We investigated the effect of different levels of smoking and drinking on the development of
squamous cell carcinoma of head and neck (HNSCC) and performed analyses to evaluate …

BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage,
including oxidative lesions that are removed effectively by the base‐excision repair (BER) …