XRCC1, XRCC3, and XPD Polymorphisms as Modifiers of the Effect of Smoking and Alcohol on Colorectal Adenoma Risk
Using a sigmoidoscopy-based case-control study (753 cases, 799 controls) in Los Angeles
County, we investigated the potential modifier role in the effect of alcohol and smoking of …
County, we investigated the potential modifier role in the effect of alcohol and smoking of …
The association between RAD18 Arg302Gln polymorphism and the risk of human non-small-cell lung cancer
H Kanzaki, M Ouchida, H Hanafusa… - Journal of cancer …, 2008 - Springer
Purpose The repair enzyme RAD18 plays a key role in the post-replication repair process in
various organisms from yeast to human, and the molecular function of the RAD18 protein …
various organisms from yeast to human, and the molecular function of the RAD18 protein …
The association of sequence variants in DNA repair and cell cycle genes with cancers of the upper aerodigestive tract
J Hall, M Hashibe, P Boffetta, V Gaborieau… - …, 2007 - academic.oup.com
Cancers of the upper aerodigestive tract (UADT), comprising the oral cavity, pharynx, larynx
and oesophagus, account for 5.2% of all cancers cases worldwide. The major risk factors …
and oesophagus, account for 5.2% of all cancers cases worldwide. The major risk factors …
Common genetic variants related to genomic integrity and risk of papillary thyroid cancer
G Neta, AV Brenner, EM Sturgis, RM Pfeiffer… - …, 2011 - academic.oup.com
DNA damage is an important mechanism in carcinogenesis, so genes related to maintaining
genomic integrity may influence papillary thyroid cancer (PTC) risk. Candidate gene studies …
genomic integrity may influence papillary thyroid cancer (PTC) risk. Candidate gene studies …
[HTML][HTML] CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
CM Gao, T Takezaki, JZ Wu, MB Chen… - World Journal of …, 2007 - ncbi.nlm.nih.gov
AIM: To investigate associations between the Rsa I polymorphism of CYP2E1 and risk of
colorectal cancer. METHODS: A case-control study was conducted with 315 colorectal …
colorectal cancer. METHODS: A case-control study was conducted with 315 colorectal …
Genetic polymorphisms in DNA repair genes and their association with cervical cancer
Background and objective: Carcinoma of cervix is the second most common cancer among
women worldwide. The DNA repair network plays an important role in the maintenance of …
women worldwide. The DNA repair network plays an important role in the maintenance of …
[PDF][PDF] The association between plymorphisms of the RAD51-G135C, XRCC2-Arg188His and XRCC3-Thr241Met genes and clinico-pathologic features in breast …
H Romanowicz-Makowska, B Smolarz… - European Journal of …, 2012 - oss.ejgo.net
Background: XRCC2 and XRCC3 genes are structurally and functionally related to RAD51
which plays an important role in homologous recombination, the process frequently involved …
which plays an important role in homologous recombination, the process frequently involved …
Allelic variants of XRCC1 and XRCC3 repair genes and susceptibility of oral cancer in Brazilian patients
MB Dos Reis, R Losi‐Guembarovski… - Journal of oral …, 2013 - Wiley Online Library
J Oral Pathol Med (2013) 42: 180–185 Background: The capacity for DNA repair is essential
in maintaining cellular functions and homeostasis; however, this capacity can be altered …
in maintaining cellular functions and homeostasis; however, this capacity can be altered …
Genetic association and functional studies of major polymorphic variants of MGMT
The DNA repair protein, O6-methylguanine DNA-methyltransferase (MGMT) prevents
mutations and cell death that result from aberrant alkylation of DNA. The polymorphic …
mutations and cell death that result from aberrant alkylation of DNA. The polymorphic …
Effects of O6-methylguanine-DNA methyltransferase (MGMT) polymorphisms on cancer: a meta-analysis
O 6-methylguanine-DNA methyltransferase is one of the rare proteins to directly remove
alkylating agents in the human DNA direct reversal repair pathway. Its two common single …
alkylating agents in the human DNA direct reversal repair pathway. Its two common single …