Smoking modifies the relationship between XRCC1 haplotypes and HPV16‐negative head and neck squamous cell carcinoma

KM Applebaum, MD McClean… - … journal of cancer, 2009 - Wiley Online Library
Reports on the relationship between head and neck squamous cell carcinoma (HNSCC)
and polymorphisms in X‐ray cross complementing group 1 (XRCC1) have been …

Genetic polymorphisms in key DNA repair genes and risk of head and neck cancer in a Chinese population

H Yuan, H Li, H Ma, Y Niu, Y Wu… - Experimental and …, 2012 - spandidos-publications.com
Although tobacco and alcohol consumption are the major risk factors of head and neck
cancer (HNC), genetic variations of genes involved in several biological pathways, such as …

[HTML][HTML] XRCC3 and NBS1 gene polymorphisms modulate the risk of pre-oral cancer and oral cancer in the North Indian population

K Nigam, S Gupta, N Singh, SK Yadav… - Journal of cancer …, 2023 - journals.lww.com
Background: Oral cancer is alarming disease in the developing countries like India. DNA
repair capacity may affect by genetic polymorphisms in DNA repair genes and thus may …

[HTML][HTML] DNA polymorphism and risk of esophageal squamous cell carcinoma in a population of North Xinjiang, China

WJ Ma, GD Lv, ST Zheng, CG Huang… - World Journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To investigate the role of metabolic enzyme and DNA repair genes in susceptibility of
esophageal squamous cell carcinoma (ESCC). METHODS: A case-control study was …

Influence of Arg399Gln, Arg280His and Arg194Trp XRCC1 gene polymorphisms of Base Excision Repair pathway on the level of 8-oxo-guanine and risk of head and …

J Kabzinski, M Maczynska, D Kaczmarczyk… - Cancer …, 2021 - content.iospress.com
BACKGROUND: Reduced efficiency of DNA repair systems has long been a suspected
factor in increasing the risk of cancer. OBJECTIVE: In this work we investigate influence of …

A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage

P Danoy, E Sonoda, M Lathrop, S Takeda… - … and biophysical research …, 2007 - Elsevier
Homologous recombination, a major double strand break repair pathway, plays critical roles
in maintaining genome stability. Genetic polymorphisms in HR genes have been implicated …

Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population

S Mukherjee, AD Bhowmik… - Journal of oral …, 2012 - Wiley Online Library
J Oral Pathol Med (2012) 41: 292–302 Background: Arecanut and smokeless tobacco usage
is a major cause for oral submucous fibrosis (OSF) and its subsequent development to oral …

XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: A meta‐analysis

H Sun, Y Qiao, X Zhang, L Xu, X Jia, D Sun… - Cancer …, 2010 - Wiley Online Library
Several studies have investigated the associations between X‐ray repair cross‐
complementing group 3 (XRCC3) Thr241Met polymorphism and the susceptibility to lung …

DNA Sequence Context Affects Repair of the Tobacco-Specific Adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by Human O6-Alkylguanine-DNA Alkyltransferases

RS Mijal, S Kanugula, CC Vu, Q Fang, AE Pegg… - Cancer research, 2006 - AACR
The repair protein O 6-alkylguanine-DNA alkyltransferase (AGT) protects cells from the
mutagenic and carcinogenic effects of alkylating agents by removing O 6-alkylguanine …

Pharmacogenetic research activity in Central America and the Caribbean: a systematic review

C Cespedes-Garro, MEG Naranjo… - …, 2016 - Taylor & Francis
Aim: The present review was aimed at analyzing the pharmacogenetic scientific activity in
Central America and the Caribbean. Materials & methods: A literature search for …