Background A paradigm shift away from clinician-led management of people with chronic
disorders to people playing a key role in their own care has been advocated. At the same …

Introduction Painful lumbar spinal disorders represent a leading cause of disability in the US
and worldwide. Interventional treatments for lumbar disorders are an effective treatment for …

Purpose Low back pain (LBP) is one of the most prevalent health condition worldwide and
responsible for the most years lived with disability, yet the etiology is often unknown …

Objective To assess the efficacy of three months of antibiotic treatment compared with
placebo in patients with chronic low back pain, previous disc herniation, and vertebral …

Back and neck pain have become a primary cause of disability and healthcare spending
globally. While the causes of back pain are multifactorial, intervertebral disc degeneration is …

The cartilaginous endplates (CEP) are key components of the intervertebral disc (IVD)
necessary for sustaining the nutrition of the disc while distributing mechanical loads and …

Study Design. A cross-sectional study of the Northern Finland Birth Cohort 1966
(NFBC1966). Objective. The aim of this study was to evaluate the association between the …

Background Estimating the contribution of endplate oedema known as Modic changes to
lower back pain (LBP) has been the subject of multiple observational studies and reviews …

Objective Lumbar degenerative spinal ailments are the most important causes for chronic
low back pain. Modic changes (MC) are vertebral bone marrow signal intensity changes …

To provide an up‐to‐date description of knowledge and pitfalls related to the classification,
definition and grading of Modic changes (MC) visualized on magnetic resonance imaging …