Drug-induced liver injury in 2007
W Norris, AH Paredes, JH Lewis - Current opinion in …, 2008 - journals.lww.com
The year 2007 brought with it several reminders of the importance of drug-induced liver
injury in the clinical trial as well as the clinical practice setting. There is additional evidence …
injury in the clinical trial as well as the clinical practice setting. There is additional evidence …
Delivery of drugs, growth factors, genes and stem cells via intrapericardial, epicardial and intramyocardial routes for sustained local targeted therapy of myocardial …
M Maslov, S Foianini, M Lovich - Expert Opinion on Drug Delivery, 2017 - Taylor & Francis
Introduction: Local myocardial delivery (LMD) of therapeutic agents is a promising strategy
that aims to treat various myocardial pathologies. It is designed to deliver agents directly to …
that aims to treat various myocardial pathologies. It is designed to deliver agents directly to …
Prediction of the dose range for adverse neurological effects of amiodarone in patients from an in vitro toxicity test by in vitro–in vivo extrapolation
Amiodarone is an antiarrhythmic agent inducing adverse effects on the nervous system,
among others. We applied physiologically based pharmacokinetic (PBPK) modeling …
among others. We applied physiologically based pharmacokinetic (PBPK) modeling …
[PDF][PDF] Visual Disturbance in a Patient with Amiodarone Treatment Following Refractive Surgery
Amiodarone is an antiarrhythmic medication used to treat a number of irregular heartbeats.
Known ocular side effects of amiodarone include visual loss, swelling of the optic disc …
Known ocular side effects of amiodarone include visual loss, swelling of the optic disc …
Permeabilized cryopreserved human hepatocytes as an exogenous metabolic system in a novel metabolism-dependent cytotoxicity assay for the evaluation of …
H Wei, AP Li - Drug Metabolism and Disposition, 2022 - ASPET
We report here a novel in vitro experimental system, the metabolism-dependent cytotoxicity
assay (MDCA), for the definition of the roles of hepatic drug metabolism in toxicity. MDCA …
assay (MDCA), for the definition of the roles of hepatic drug metabolism in toxicity. MDCA …
[HTML][HTML] Acute hepatitis secondary to parenteral amiodarone does not preclude subsequent oral therapy
M Lahbabi, N Aqodad, A Ibrahimi… - World Journal of …, 2012 - ncbi.nlm.nih.gov
Amiodarone chlorhydrate is a diiodated benzofuran derivative used to treat cardiac rhythm
abnormalities. Hepatotoxicity is a relatively uncommon side effect of amiodarone and …
abnormalities. Hepatotoxicity is a relatively uncommon side effect of amiodarone and …
Assessing the risk for peripheral neuropathy in patients treated with dronedarone compared with that in other antiarrhythmics
C Wu, S Tcherny-Lessenot, W Dai, Y Wang… - Clinical …, 2018 - Elsevier
Purpose There are few data on the risk for peripheral neuropathy associated with
dronedarone, a newer antiarrhythmic medicine. The objective of this study was to assess …
dronedarone, a newer antiarrhythmic medicine. The objective of this study was to assess …
[PDF][PDF] Gastrointestinal side effects of antiarrhythmic medications: a review of current literature
W Amjad, W Qureshi, A Farooq, U Sohail, S Khatoon… - Cureus, 2017 - cureus.com
Antiarrhythmic drugs are commonly prescribed cardiac drugs. Due to their receptor mimicry
with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal …
with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal …
Amiodarone‐Induced Nystagmus and Ataxia: Case Report and Systematic Review of Case Reports
P Kaur, A Kaur, A Sinha, W Khaliq… - The Journal of …, 2023 - Wiley Online Library
Amiodarone is an antiarrhythmic drug with a significant adverse effect profile, including
neurotoxicity. While ataxia, neuropathy, and tremors are more commonly seen forms of …
neurotoxicity. While ataxia, neuropathy, and tremors are more commonly seen forms of …
[HTML][HTML] The incidence and predictors of overall adverse effects caused by low dose amiodarone in real-world clinical practice
HL Kim, JB Seo, WY Chung, SH Kim… - The Korean Journal of …, 2014 - ncbi.nlm.nih.gov
Methods Between January 1, 2000 and March 10, 2012, a total of 930 consecutive patients
who had been treated with amiodarone for arrhythmia were reviewed retrospectively. An …
who had been treated with amiodarone for arrhythmia were reviewed retrospectively. An …