Serotonin modulates many motivated behaviours via multiple receptor subtypes. Agonists at
5-HT 2 C receptors have potential for treating behavioural problems associated with obesity …

The implication of 5-hydroxytryptamine 2C receptor (5-HT2CR) in depression is a topic of
debate, and the underlying mechanisms remain largely unclear. We now elucidate …

The infralimbic cortex (IL) is part of the medial prefrontal cortex (mPFC), exerting top-down
control over structures that are critically involved in the development of alcohol use disorder …

The serotonin 2C receptor subtype (5-HT2C) is an excitatory 5-HT receptor widely
distributed throughout the central nervous system. As the 5-HT2C receptor displays multiple …

Major depressive disorder is a severe mood disorder associated with a marked decrease in
quality of life and social functioning, accompanied by a risk of suicidal behavior. Therefore …

The last fifteen years have seen the emergence and overflow into the drug scene of
“superpotent” N-benzylated phenethylamines belonging to the “NBOMe” series …

Aporphine alkaloids have shown affinity for serotonin receptors (5-HTRs), and there has
been a recent upsurge of interest in aporphines as 5-HT2CR ligands. 1, 2, 9, 10 …

Serotonin (5-HT) is important in some nicotine actions in the CNS. Among all the 5-HT
receptors (5-HTRs), the 5-HT2CR has emerged as a promising drug target for smoking …

Abstract The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) modulates fundamental
motivational processes, and the neurochemical and behavioural effects of drugs of abuse …

Abstract The serotonin (5-HT) 2 C receptor (R) is a widely distributed G-protein-coupled
receptor, expressed abundantly in the central nervous system. Alstonine is a natural product …