SA-AKI is a common condition that can involve disturbances in the RAS, particularly the
canonical angiotensin-converting enzyme (ACE) angiotensin-II (Ang II)/angiotensin II …

Cardiovascular disease is the leading cause of death globally among non-communicable
diseases, which imposes a serious socioeconomic burden on patients and the healthcare …

The study of enzymes never disappoints. Despite its long history—almost 150 years
following the first documented use of the word enzyme in 1878—the field of enzymology …

Pancreatic adenocarcinoma (PDAC) is highly resistant to conventional chemotherapeutic
interventions, resulting in exceptionally low survival rates. The limited efficacy can in part be …

Recent evidence highlights the importance of trace metal micronutrients such as zinc (Zn) in
coronary and vascular diseases. Zn2+ plays a signalling role in modulating endothelial nitric …

The renin–angiotensin system (RAS) plays a crucial role in regulating blood pressure and
the cardio-renal system. The classical RAS, mainly mediated by angiotensin I, angiotensin …

Dipeptidyl peptidase III (DPP3) is a ubiquitously expressed zinc-dependent peptide cutting
enzyme and selectively hydrolyses amide bonds to cleave N-terminal dipeptide fragments …

The dipeptidyl peptidase 3 (Dpp3) is a ubiquitous zinc-dependent aminopeptidase,
participating in the activation or degradation of signaling peptides and in the Keap1–Nrf2 …

Abstract Dipeptidyl peptidase III (DPP III) is a cytosolic, two-domain zinc-exopeptidase. It is
widely distributed in mammalian tissues, where it's involved in the final steps of normal …

The renin-angiotensin system (RAS) constitutes one of the principal mechanisms to maintain
hemodynamic and fluid homeostasis. However, most research until now on RAS primarily …