Long noncoding RNAs (lncRNAs) have gained widespread attention in recent years as a
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …

Long noncoding RNAs (lncRNAs) are the major elements of the mammalian transcriptome
that is emerging as a central player controlling diverse cellular mechanisms. Most of the well …

A-to-I RNA editing, the deamination of adenosine (A) to inosine (I) that occurs in regions of
RNA with double-stranded character, is catalyzed by a family of Adenosine Deaminases …

C6 deamination of adenosine (A) to inosine (I) in double-stranded RNA (dsRNA) is
catalyzed by a family of enzymes known as ADARs (adenosine deaminases acting on RNA) …

MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression at the post-
transcriptional level. Through this activity, they are implicated in almost every cellular …

Double-stranded RNA (dsRNA) functions both as a substrate of ADARs and also as a
molecular trigger of innate immune responses. ADARs, adenosine deaminases that act on …

Merkel cell polyomavirus (MCPyV) is considered the etiological agent of Merkel cell
carcinoma and persists asymptomatically in the majority of its healthy hosts. Largely due to …

Caenorhabditis elegans mutants deleted for TDP‐1, an ortholog of the neurodegeneration‐
associated RNA‐binding protein TDP‐43, display only mild phenotypes. Nevertheless …

The conversion of genomically encoded adenosine to inosine in dsRNA is termed as A‐to‐I
RNA editing. This process is catalyzed by two of the three mammalian ADAR proteins …

Signaling through retinoic acid inducible gene I (RIG-I) like receptors (RLRs) is tightly
regulated, with activation occurring upon sensing of viral nucleic acids, and suppression …