Omics approaches for the assessment of biological responses to nanoparticles

Y Abdelkader, L Perez-Davalos, R LeDuc… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology has enabled the development of innovative therapeutics, diagnostics, and
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …

Nanoparticles‐induced potential toxicity on human health: applications, toxicity mechanisms, and evaluation models

L Xuan, Z Ju, M Skonieczna, PK Zhou, R Huang - MedComm, 2023 - Wiley Online Library
Nanoparticles (NPs) have become one of the most popular objects of scientific study during
the past decades. However, despite wealth of study reports, still there is a gap, particularly in …

Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)

G Gupta, F Cappellini, L Farcal, R Gornati… - Particle and Fibre …, 2022 - Springer
Abstract Background Copper oxide (CuO) nanoparticles (NPs) are known to trigger
cytotoxicity in a variety of cell models, but the mechanism of cell death remains unknown …

The toxicity of nanoparticles and their interaction with cells: an in vitro metabolomic perspective

M Awashra, P Młynarz - Nanoscale Advances, 2023 - pubs.rsc.org
Nowadays, nanomaterials (NMs) are widely present in daily life due to their significant
benefits, as demonstrated by their application in many fields such as biomedicine …

Simulated biological fluids–a systematic review of their biological relevance and use in relation to inhalation toxicology of particles and fibres

E Innes, HHP Yiu, P McLean, W Brown… - Critical Reviews in …, 2021 - Taylor & Francis
The use of simulated biological fluids (SBFs) is a promising in vitro technique to better
understand the release mechanisms and possible in vivo behaviour of materials, including …

Paradigms to assess the human health risks of nano-and microplastics

S Noventa, MSP Boyles, A Seifert, S Belluco… - Microplastics and …, 2021 - Springer
Human exposure to nano-and microplastics (NMPs) has raised major societal concerns, yet
no framework to assess the risks of NMPs for human health exists. A substantial proportion …

Copper nanoparticles as an alternative feed additive in poultry diet: a review

A Scott, KP Vadalasetty, A Chwalibog… - Nanotechnology …, 2018 - degruyter.com
Copper (Cu) is a vital trace element involved in various physiological and biochemical
processes. However, animals can only absorb a small fraction of Cu and the most is …

Oxidative stress-and mitochondrial dysfunction-mediated cytotoxicity by silica nanoparticle in lung epithelial cells from metabolomic perspective

X Zhao, A Abulikemu, S Lv, Y Qi, J Duan, J Zhang… - Chemosphere, 2021 - Elsevier
Quantities of researches have demonstrated silica nanoparticles (SiNPs) exposure
inevitably induced damage to respiratory system, nonetheless, knowledge of its toxicological …

Role of omics techniques in the toxicity testing of nanoparticles

E Fröhlich - Journal of nanobiotechnology, 2017 - Springer
Nanotechnology is regarded as a key technology of the twenty-first century. Despite the
many advantages of nanotechnology it is also known that engineered nanoparticles (NPs) …

Lysosomal deposition of copper oxide nanoparticles triggers HUVEC cells death

J Zhang, Z Zou, B Wang, G Xu, Q Wu, Y Zhang, Z Yuan… - Biomaterials, 2018 - Elsevier
Abstracts The increasing use of copper oxide nanoparticles (CuONPs) has led to major
concerns regarding both the predominant physicochemical properties and the potential toxic …