Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action

CH Storch, PH Hoeger - British Journal of Dermatology, 2010 - academic.oup.com
Infantile haemangiomas (IH) are the most common benign tumours of infancy. Although
most IH are innocuous and 85–90% regress spontaneously, some may become life‐or …

The effectiveness of propranolol in treating infantile haemangiomas: a meta‐analysis including 35 studies

Y Lou, W Peng, Y Cao, D Cao, J Xie… - British journal of clinical …, 2014 - Wiley Online Library
Aims Propranolol may have shown excellent results as a first line therapy in infantile
haemangiomas (IHs) at all sites in the body, but this conclusion remains controversial. In an …

Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies

A Munden, R Butschek, WL Tom… - British Journal of …, 2014 - academic.oup.com
Background The aetiology and exact incidence of infantile haemangiomas (IHs) are
unknown. Prior studies have noted immunohistochemical and biological characteristics …

Propranolol treatment for hemangioma of infancy: risks and recommendations

LP Lawley, E Siegfried, JL Todd - Pediatric dermatology, 2009 - Wiley Online Library
Hemangioma of infancy is a condition that may be associated with significant morbidity.
While evidence most supports the use of corticosteroids, there is no well‐defined or Federal …

A prospective study of infantile hemangiomas with a focus on incidence and risk factors

P Dickison, E Christou, O Wargon - Pediatric dermatology, 2011 - Wiley Online Library
Infantile hemangiomas (IHs) are the most common tumor of infancy and have been
estimated to occur in 4% of infants. Only two previous incidence studies of IH in a healthy …

[HTML][HTML] VEGFR-2 conformational switch in response to ligand binding

S Sarabipour, K Ballmer-Hofer, K Hristova - Elife, 2016 - elifesciences.org
VEGFR-2 is the primary regulator of angiogenesis, the development of new blood vessels
from pre-existing ones. VEGFR-2 has been hypothesized to be monomeric in the absence of …

Propranolol versus prednisone in the treatment of infantile hemangiomas: a retrospective comparative study

J Bertrand, C McCuaig, J Dubois, A Hatami… - Pediatric …, 2011 - Wiley Online Library
The goal of the current study was to compare the clinical effectiveness of oral propranolol
with that of oral prednisone in the treatment of infantile hemangiomas (IH). Patients treated …

Recent progress in studies of infantile hemangioma

M Jinnin, T Ishihara, E Boye… - The Journal of …, 2010 - Wiley Online Library
A hallmark of infantile hemangioma, the most common tumor of infancy, is its dramatic
growth after birth, by diffuse proliferation of immature endothelial cells, followed by …

Propranolol for infantile hemangiomas: promise, peril, pathogenesis.

IJ Frieden, BA Drolet - Pediatric dermatology, 2009 - search.ebscohost.com
The article presents the author's views regarding the usage of propranolol as a treatment for
infantile hemangiomas. He says the propranolol is a non-selective beta-blocker which have …

Multimodality imaging of vascular anomalies

R Restrepo - Pediatric radiology, 2013 - Springer
Vascular malformations and hemangiomas are common in children but remain a source of
confusion during diagnosis, in part because of the lack of a uniform terminology. With the …