Globally, breast cancer is the most common cancer type and is one of the most significant
causes of deaths in women. To date, multiple clinical interventions have been applied …

In eukaryotic cells, the endoplasmic reticulum (ER) is an organelle that is responsible for
protein folding and assembly, lipid and sterol biosynthesis, and free calcium storage. In the …

In China, animal feeds are frequently contaminated with a range of mycotoxins, with
Aflatoxin B1 (AFB1) and T-2 toxin (T-2) being two highly toxic mycotoxins. This study …

Background: Advanced hormone-receptor positive HER2 negative breast cancer is a
common and a very heterogeneous disease. Hormone therapy is the main first line …

Background Curcumin functions as a proteasome inhibitor. However, the molecular
mechanisms behind this action need more detailed explanations. Purpose This study aimed …

The discovery of the proteasome in the late 80's as the core protease of what will be then
called the ubiquitin–proteasome system, rapidly followed by the development of specific …

The primary cilium is an essential structure for the mediation of numerous signaling
pathways involved in the coordination and regulation of cellular processes essential for the …

The endoplasmic reticulum (ER) is an interconnected organelle that is responsible for the
biosynthesis, folding, maturation, stabilization, and trafficking of transmembrane and …

By utilizing nanoparticles to upload and interact with several pharmaceuticals in varying
methods, the primary obstacles associated with loading two or more medications or cargos …

The Hedgehog signalling pathway is evolutionarily highly conserved and essential for
embryonic development of invertebrates and vertebrates. Consequently, impaired …