Pulmonary surfactant: a mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films
E Parra, J Pérez-Gil - Chemistry and physics of lipids, 2015 - Elsevier
The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …
membrane-based system composed of multiple lipids and specific proteins, the primary …
[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
Interactions of particulate matter and pulmonary surfactant: Implications for human health
F Wang, J Liu, H Zeng - Advances in colloid and interface science, 2020 - Elsevier
Particulate matter (PM), which is the primary contributor to air pollution, has become a
pervasive global health threat. When PM enters into a respiratory tract, the first body tissues …
pervasive global health threat. When PM enters into a respiratory tract, the first body tissues …
DPPC Langmuir monolayer at the air− water interface: probing the tail and head groups by vibrational sum frequency generation spectroscopy
Dipalmitoylphosphatidylcholine (DPPC) is the predominant lipid component in lung
surfactant. In this study, the Langmuir monolayer of deuterated …
surfactant. In this study, the Langmuir monolayer of deuterated …
Protein–lipid interactions and surface activity in the pulmonary surfactant system
AG Serrano, J Pérez-Gil - Chemistry and physics of lipids, 2006 - Elsevier
Pulmonary surfactant is a lipid–protein complex, synthesized and secreted by the respiratory
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …
Collapse mechanisms of Langmuir monolayers
KYC Lee - Annu. Rev. Phys. Chem., 2008 - annualreviews.org
When a two-dimensional (2D) film is compressed to its stability limit, it explores the third
dimension via collapse. Understanding this 2D-to-3D transition is of great importance as it …
dimension via collapse. Understanding this 2D-to-3D transition is of great importance as it …
[HTML][HTML] Comparing experimental and simulated pressure-area isotherms for DPPC
SL Duncan, RG Larson - Biophysical journal, 2008 - cell.com
Although pressure-area isotherms are commonly measured for lipid monolayers, it is not
always appreciated how much they can vary depending on experimental factors. Here, we …
always appreciated how much they can vary depending on experimental factors. Here, we …
Interfacial properties of pulmonary surfactant layers
R Wüstneck, J Perez-Gil, N Wüstneck, A Cruz… - Advances in colloid and …, 2005 - Elsevier
The composition of the pulmonary surfactant and the border conditions of normal human
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …
[HTML][HTML] Combined and independent action of proteins SP-B and SP-C in the surface behavior and mechanical stability of pulmonary surfactant films
The hydrophobic proteins SP-B and SP-C are essential for pulmonary surfactant function,
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …