The continuous dynamic reshaping of mitochondria by fusion and fission events is critical to
keep mitochondrial quality and function under control in response to changes in energy and …

Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from
impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy …

Background Frailty, a clinical syndrome commencing at midlife, is a risk for morbidity and
mortality. Little is known about the factors that contribute to the chronic inflammatory state …

Physical frailty and sarcopenia (PF&S) is a prototypical geriatric condition characterized by
reduced physical function and low muscle mass. The aim of the present study was to provide …

Background Whole-body electromyostimulation (WB-EMS) was never previously applied to
Parkinson's disease (PD) patients. This randomized controlled study aimed to find the most …

Mitochondrial function is fundamental to maintaining metabolic homeostasis. Alterations in
mitochondrial biogenesis, energy production, and dynamics are behind many metabolic …

The cocoa shell is a by-product that may be revalorized as a source of bioactive compounds
to prevent chronic cardiometabolic diseases. This study aimed to investigate the …

Fgf21 has been identified as playing a regulatory role in muscle growth and function.
Although the mechanisms through which endurance training regulates skeletal muscle have …

Diabetic retinopathy (DR) is one of the leading causes of blindness globally. Retinal
neuronal abnormalities occur in the early stage in DR. Therefore, maintaining retinal …

Bariatric surgeries such as the Vertical Sleeve Gastrectomy (VSG) are invasive but provide
the most effective improvements in obesity and Type 2 diabetes. We hypothesized a …