Radiation-induced inflammation and autoimmune diseases

R Yahyapour, P Amini, S Rezapour, M Cheki… - Military Medical …, 2018 - Springer
Currently, ionizing radiation (IR) plays a key role in the agricultural and medical industry,
while accidental exposure resulting from leakage of radioactive sources or radiological …

Exposing the thyroid to radiation: a review of its current extent, risks, and implications

B Sinnott, E Ron, AB Schneider - Endocrine reviews, 2010 - academic.oup.com
Radiation exposure of the thyroid at a young age is a recognized risk factor for the
development of differentiated thyroid cancer lasting for four decades and probably for a …

Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review

M Tubiana - Radiotherapy and Oncology, 2009 - Elsevier
Second primary malignancies (SPMs) occurring after oncological treatment have become a
major concern during the past decade. Their incidence has long been underestimated …

[PDF][PDF] Hydrogen peroxide induces DNA single-and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ

N Driessens, S Versteyhe, C Ghaddhab… - Endocrine-related …, 2009 - academia.edu
DNA double-strand breaks (DSBs) are considered as one of the primary causes of cancer
but their induction by hydrogen peroxide (H2O2) is still controversial. In this work, we studied …

Oxidative stress in thyroid carcinomas: biological and clinical significance

RA El Hassani, C Buffet, S Leboulleux… - Endocrine-related …, 2019 - erc.bioscientifica.com
At physiological concentrations, reactive oxygen species (ROS), including superoxide
anions and H 2 O 2, are considered as second messengers that play key roles in cellular …

Dual oxidase, hydrogen peroxide and thyroid diseases

H Ohye, M Sugawara - Experimental biology and medicine, 2010 - journals.sagepub.com
The thyroid gland is a unique endocrine organ that requires hydrogen peroxide (H2O2) for
thyroid hormone formation. The molecule for H2O2 production in the thyroid gland has been …

Review of risk factors of secondary cancers among cancer survivors

C Demoor-Goldschmidt… - The British journal of …, 2019 - academic.oup.com
Improvements in cancer survival have made the long-term risks from treatments more
important, in particular among the children, adolescents and young adults who are more at …

Association of Hashimoto's thyroiditis with thyroid cancer

G Azizi, JM Keller, M Lewis, K Piper… - Endocrine-related …, 2014 - erc.bioscientifica.com
This prospective study investigates the relationship between Hashimoto's thyroiditis (HT)
and thyroid cancer (TC) in patients with thyroid nodules (TNs). We prospectively examined …

A gene expression signature distinguishes normal tissues of sporadic and radiation-induced papillary thyroid carcinomas

G Dom, M Tarabichi, K Unger, G Thomas… - British journal of …, 2012 - nature.com
Background: Papillary thyroid cancer (PTC) incidence increased dramatically in children
after the Chernobyl accident, providing a unique opportunity to investigate the molecular …

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival

Q Zheng, SM Dunlap, J Zhu… - Endocrine-related …, 2011 - erc.bioscientifica.com
Papillary thyroid carcinoma (PTC) etiologically occurs as a radiation-induced or sporadic
malignancy. Genetic factors contributing to the susceptibility to either form remain unknown …