New insights into atypical Alzheimer's disease in the era of biomarkers
Most patients with Alzheimer's disease present with amnestic problems; however, a
substantial proportion, over-represented in young-onset cases, have atypical phenotypes …
substantial proportion, over-represented in young-onset cases, have atypical phenotypes …
Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention
YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …
insidious age-related neurodegenerative disease and is presently considered a global …
Research criteria for the behavioral variant of Alzheimer disease: a systematic review and meta-analysis
R Ossenkoppele, EH Singleton, C Groot… - JAMA …, 2022 - jamanetwork.com
Importance The behavioral variant of Alzheimer disease (bvAD) is characterized by early
and predominant behavioral deficits caused by AD pathology. This AD phenotype is …
and predominant behavioral deficits caused by AD pathology. This AD phenotype is …
The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features
R Ossenkoppele, YAL Pijnenburg, DC Perry… - Brain, 2015 - academic.oup.com
A 'frontal variant of Alzheimer's disease'has been described in patients with predominant
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …
Clinicopathological correlations in behavioural variant frontotemporal dementia
Accurately predicting the underlying neuropathological diagnosis in patients with
behavioural variant frontotemporal dementia (bvFTD) poses a daunting challenge for …
behavioural variant frontotemporal dementia (bvFTD) poses a daunting challenge for …
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
K Rascovsky, JR Hodges, D Knopman, MF Mendez… - Brain, 2011 - academic.oup.com
Based on the recent literature and collective experience, an international consortium
developed revised guidelines for the diagnosis of behavioural variant frontotemporal …
developed revised guidelines for the diagnosis of behavioural variant frontotemporal …
Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies
IRA Mackenzie, M Neumann - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The past decade has seen the discovery of several new FTD‐causing genetic …
basis. The past decade has seen the discovery of several new FTD‐causing genetic …
Classification of primary progressive aphasia and its variants
ML Gorno-Tempini, AE Hillis, S Weintraub, A Kertesz… - Neurology, 2011 - AAN Enterprises
This article provides a classification of primary progressive aphasia (PPA) and its 3 main
variants to improve the uniformity of case reporting and the reliability of research results …
variants to improve the uniformity of case reporting and the reliability of research results …
Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation
Amyloid-β, a hallmark of Alzheimer's disease, begins accumulating up to two decades
before the onset of dementia, and can be detected in vivo applying amyloid-β positron …
before the onset of dementia, and can be detected in vivo applying amyloid-β positron …
Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
K Blennow, H Hampel, M Weiner… - Nature Reviews …, 2010 - nature.com
Intense multidisciplinary research has provided detailed knowledge of the molecular
pathogenesis of Alzheimer disease (AD). This knowledge has been translated into new …
pathogenesis of Alzheimer disease (AD). This knowledge has been translated into new …