Neutrophils are increasingly recognized as key players in the tumor immune response and
are associated with poor clinical outcomes. Despite recent advances characterizing the …

Metastasis is the main cause of cancer-related mortality. Although the actual process of
metastasis remains largely elusive, epithelial-mesenchymal transition (EMT) has been …

The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

Tumor-associated macrophages have emerged as crucial factors for metastases. Microglia
are indispensable components of the brain microenvironment and play vital roles in brain …

Glioma is the prime cause of cancer allied mortality in adolescent people and it accounts
about 80% of all malignant tumours. Eugenol is a major bioactive constituent present in the …

Metabolism rewiring is an important hallmark of cancers. Being one of the most abundant
free amino acids in the human blood, glutamine supports bioenergetics and biosynthesis …

Phenotypic plasticity associated with the hybrid epithelial–mesenchymal transition (EMT) is
crucial to metastatic seeding and outgrowth. However, the mechanisms governing the hybrid …

Metabolic constraints in the tumor microenvironment constitute a barrier to effective
antitumor immunity and similarities in the metabolic properties of T cells and cancer cells …

Besides molecular and phenotypic variations observed in cancer cells, intratumoral
heterogeneity also occurs in the tumor microenvironment. Correlative stiffness maps of …

Cancer is a fatal disease with a complex pathophysiology. Lack of specificity and
cytotoxicity, as well as the multidrug resistance of traditional cancer chemotherapy, are the …