The Global Initiative for Asthma guidelines use the traditional terminology of “low,”“medium,”
and “high” doses of inhaled corticosteroids (ICS) to define daily maintenance doses of 100 …

Background Inhaled corticosteroids (ICS) form the basis of maintenance therapy in asthma
and their efficacy is well established. However, the optimal starting dose of ICS is not clearly …

The aim of this study was to examine the dose-response relationship of inhaled budesonide
in adolescents and adults with asthma. A meta-analysis was carried out on placebo …

Background While most of the clinical benefits of inhaled corticosteroid (ICS) therapy may
occur at low doses, results of dose-ranging studies are inconsistent. Although symptom/lung …

Abstract Background Inhaled corticosteroids (ICSs) are recommended as first-line controller
medications for persistent asthma. However, guidelines on the initial ICS doses, step-up and …

Patients with mild persistent asthma rarely see their doctor with symptoms of the disease.
Partly as a result of this situation, mild asthma is generally undertreated. Findings of several …

The distribution of responses in study populations provides a novel method of comparing the
benefit of two treatments. This 6‐week, randomised, placebo-controlled, double-blind study …

Background Asthma is a condition of the airways affecting more than 300 million adults and
children worldwide. National and international guidelines recommend titrating up the dose …

Background: Asthma guidelines vary in their recommendations for the initial dose of inhaled
corticosteroid (ICS) in asthma. A systematic review of the literature was conducted to …

Dose-dependent effects of inhaled corticosteroids have been described. Although it has
been advised to start treatment with inhaled corticosteroids with a high dose tapering off …