Leukocytes link local and systemic inflammation in ischemic cardiovascular disease: an expanded “cardiovascular continuum”

P Libby, M Nahrendorf, FK Swirski - Journal of the American College of …, 2016 - jacc.org
Physicians have traditionally viewed ischemic heart disease in a cardiocentric manner:
plaques grow in arteries until they block blood flow, causing acute coronary and other …

Atherosclerosis: the interplay between lipids and immune cells

F Schaftenaar, V Frodermann, J Kuiper… - Current opinion in …, 2016 - journals.lww.com
Atherosclerosis: the interplay between lipids and immune cel... : Current Opinion in Lipidology
Atherosclerosis: the interplay between lipids and immune cells : Current Opinion in Lipidology …

[HTML][HTML] Defining natural antibodies

NE Holodick, N Rodríguez-Zhurbenko… - Frontiers in …, 2017 - frontiersin.org
The traditional definition of natural antibodies (NAbs) states that these antibodies are
present prior to the body encountering cognate antigen, providing a first line of defense …

ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies

C Lorenzo, P Delgado, CE Busse, A Sanz-Bravo… - Nature, 2021 - nature.com
Cardiovascular disease (CVD) is the leading cause of mortality in the world, with most CVD-
related deaths resulting from myocardial infarction or stroke. The main underlying cause of …

Oxidized LDL and anti-oxidized LDL antibodies in atherosclerosis–novel insights and future directions in diagnosis and therapy

A Hartley, D Haskard, R Khamis - Trends in Cardiovascular Medicine, 2019 - Elsevier
We provide an up-to-date overview of current topics surrounding oxidized low-density
lipoprotein (oxLDL) and its related antibodies in the quest to better identify the individuals at …

Role of p38 MAPK in atherosclerosis and aortic valve sclerosis

A Reustle, M Torzewski - International journal of molecular sciences, 2018 - mdpi.com
Atherosclerosis and aortic valve sclerosis are cardiovascular diseases with an increasing
prevalence in western societies. Statins are widely applied in atherosclerosis therapy …

Role of inflammation and immunity in hypertension: recent epidemiological, laboratory, and clinical evidence

A Caillon, EL Schiffrin - Current hypertension reports, 2016 - Springer
Inflammation has been shown to play an important role in the mechanisms involved in the
pathogenesis of hypertension. Accordingly, innate and adaptive immune responses …

Novel antiatherosclerotic therapies

P Libby, BM Everett - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Many measures can control lipid risk factors for atherosclerosis. Yet, even with excellent
control of dyslipidemia, other sources of risk remain. Hence, we must look beyond lipids to …

Crossing the vascular wall: common and unique mechanisms exploited by different leukocyte subsets during extravasation

M Schnoor, P Alcaide, MB Voisin… - Mediators of …, 2015 - Wiley Online Library
Leukocyte extravasation is one of the essential and first steps during the initiation of
inflammation. Therefore, a better understanding of the key molecules that regulate this …

Immunological memory cells

W Ratajczak, P Niedźwiedzka-Rystwej… - … European Journal of …, 2018 - termedia.pl
This article reviews immunological memory cells, currently represented by T and B
lymphocytes and natural killer (NK) cells, which determine a rapid and effective response …