Sialic acid metabolism as a potential therapeutic target of atherosclerosis

C Zhang, J Chen, Y Liu, D Xu - Lipids in health and disease, 2019 - Springer
Sialic acid (Sia), the acylated derivative of the nine-carbon sugar neuraminic acid, is a
terminal component of the oligosaccharide chains of many glycoproteins and glycolipids. In …

Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European …

J Tunon, L Badimon, ML Bochaton-Piallat… - Cardiovascular …, 2019 - academic.oup.com
Dysregulated lipid metabolism induces an inflammatory and immune response leading to
atherosclerosis. Conversely, inflammation may alter lipid metabolism. Recent treatment …

Malondialdehyde epitopes as targets of immunity and the implications for atherosclerosis

N Papac-Milicevic, CJL Busch, CJ Binder - Advances in immunology, 2016 - Elsevier
Accumulating evidence suggests that oxidation-specific epitopes (OSEs) constitute a novel
class of damage-associated molecular patterns (DAMPs) generated during high oxidative …

[HTML][HTML] Modified lipoproteins induce arterial wall inflammation during atherogenesis

MB Lorey, K Öörni, PT Kovanen - Frontiers in cardiovascular …, 2022 - frontiersin.org
Circulating apolipoprotein B-containing lipoproteins, notably the low-density lipoproteins,
enter the inner layer of the arterial wall, the intima, where a fraction of them is retained and …

[HTML][HTML] The influence of dysfunctional signaling and lipid homeostasis in mediating the inflammatory responses during atherosclerosis

ML Buckley, DP Ramji - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Atherosclerosis, the underlying cause of myocardial infarction and thrombotic
cerebrovascular events, is responsible for the majority of deaths in westernized societies …

Follicular B cells promote atherosclerosis via T cell–mediated differentiation into plasma cells and secreting pathogenic immunoglobulin G

C Tay, YH Liu, P Kanellakis, A Kallies, Y Li… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—B cells promote or protect development of atherosclerosis. In this study, we
examined the role of MHCII (major histocompatibility II), CD40 (cluster of differentiation 40) …

[HTML][HTML] The regulation of immune cells by Lactobacilli: a potential therapeutic target for anti-atherosclerosis therapy

YH Ding, LY Qian, J Pang, JY Lin, Q Xu, LH Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Atherosclerosis is an inflammatory disease regulated by several immune cells including
lymphocytes, macrophages and dendritic cells. Gut probiotic bacteria like Lactobacilli have …

Targeting B cells in atherosclerosis: closing the gap from bench to bedside

D Tsiantoulas, AP Sage, Z Mallat… - … thrombosis, and vascular …, 2015 - Am Heart Assoc
Atherosclerotic plaque formation is strongly influenced by different arms of the immune
system, including B lymphocytes. B cells are divided into 2 main families: the B1 and the B2 …

The impact of type 2 immunity and allergic diseases in atherosclerosis

N Fernández‐Gallego, R Castillo‐González… - Allergy, 2022 - Wiley Online Library
Allergic diseases are allergen‐induced immunological disorders characterized by the
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …

[HTML][HTML] Anti-inflammatory nanomedicine for cardiovascular disease

S Katsuki, T Matoba, J Koga, K Nakano… - Frontiers in …, 2017 - frontiersin.org
Coronary artery disease, in the development of which inflammation mediated by innate
immune cells plays a critical role, is one of the leading causes of death worldwide. The 3 …