Oxidation-specific epitopes (OSEs) present on apoptotic cells and oxidized low density
lipoprotein (OxLDL) represent danger-associated molecular patterns that are recognized by …

Primarily a consequence of sedentary lifestyle, atherosclerosis has already reached
pandemic proportions, and with every year the burden of it is only increasing. As low-density …

B cells are traditionally known for their ability to produce antibodies in the context of adaptive
immune responses. However, over the last decade B cells have been increasingly …

Objective—Explore aorta B-cell immunity in aged apolipoprotein E-deficient (ApoE−/−) mice.
Approach and Results—Transcript maps, fluorescence-activated cell sorting …

The prevalence of non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis
to inflammatory steatohepatitis (NASH) and cirrhosis, continues to rise, making it one of the …

Aims Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting
in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte …

Atherosclerosis is believed to be a chronic inflammation of the arterial wall and various
immune cells of innate and adaptive immunity involves in the pathogenesis of …

Objective—Small-molecule hypoxia-inducible factor prolyl 4-hydroxylase (HIF-P4H)
inhibitors are being explored in clinical studies for the treatment of anemia. HIF-P4H-2 (also …

Inflammation is a crucial part of the healing process after an ischemic stroke and is required
to restore tissue homeostasis. However, the inflammatory response to stroke also worsens …

Background: Atherosclerosis progression is modulated by interactions with the adaptive
immune system. Humoral immunity can help protect against atherosclerosis formation; …