Innate and adaptive immune cell subsets as risk factors for coronary heart disease in two population-based cohorts

NC Olson, CM Sitlani, MF Doyle, SA Huber, AL Landay… - Atherosclerosis, 2020 - Elsevier
Background and aims Cell-mediated immunity is implicated in atherosclerosis. We
evaluated whether innate and adaptive immune cell subsets in peripheral blood are risk …

Nanomaterials to resolve atherosclerosis

EB Peters, MR Kibbe - ACS Biomaterials Science & Engineering, 2020 - ACS Publications
Cardiovascular disease is the leading cause of death and disability in the world.
Atherosclerosis, the buildup of fatty deposits in arteries, is a major underlying cause …

Impact of B-cell–targeted therapies on cardiovascular disease

F Porsch, CJ Binder - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Atherosclerosis is a lipid-driven chronic inflammatory disease that is modulated by many
immune cell subsets, including B cells. Therefore, targeting the inflammatory component of …

Role of B lymphocytes in the infarcted mass in patients with acute myocardial infarction

ACA Casarotti, D Teixeira, IM Longo-Maugeri… - Bioscience …, 2021 - portlandpress.com
Despite early reperfusion, patients with ST segment elevation myocardial infarction (STEMI)
may present large myocardial necrosis and significant impairment of ventricular function …

[HTML][HTML] Immune-mediated inflammation in vulnerable atherosclerotic plaques

H Mangge, G Almer - Molecules, 2019 - mdpi.com
Atherosclerosis is a chronic long-lasting vascular disease leading to myocardial infarction
and stroke. Vulnerable atherosclerotic (AS) plaques are responsible for these life …

Regulation of transcription factors by reactive oxygen species and nitric oxide in vascular physiology and pathology

S Kohlgrüber, A Upadhye, N Dyballa-Rukes… - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Cardiovascular diseases are the main cause of death worldwide and pose an
immense economical burden. In most cases, the underlying problem is vascular occlusion …

[HTML][HTML] New Insights into Pathophysiology and New Risk Factors for ACS

M Nardin, M Verdoia, N Laera, D Cao… - Journal of Clinical …, 2023 - mdpi.com
Cardiovascular disease still represents the main cause of mortality worldwide. Despite huge
improvements, atherosclerosis persists as the principal pathological condition, both in stable …

[HTML][HTML] Gut microbiota and atherosclerosis: role of B cell for atherosclerosis focusing on the gut-immune-B2 cell axis

L Chen, T Ishigami, H Doi, K Arakawa… - Journal of Molecular …, 2020 - Springer
Atherosclerosis is the leading cause of cardiovascular mortality and morbidity worldwide
and is described as a complex disease involving several different cell types and their …

The role of immune mechanisms in alcoholic and nonalcoholic steatohepatitis: a 2015 update

S Sutti, S Bruzzì, E Albano - Expert Review of Gastroenterology & …, 2016 - Taylor & Francis
So far, innate immune mechanisms have been recognized as the main responsible for the
evolution of both alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH) …

[HTML][HTML] High serum immunoglobulin G and M levels predict freedom from adverse cardiovascular events in hypertension: a nested case-control substudy of the Anglo …

RY Khamis, AD Hughes, M Caga-Anan, CL Chang… - …, 2016 - thelancet.com
Aims We aimed to determine whether the levels of total serum IgM and IgG, together with
specific antibodies against malondialdehyde-conjugated low-density lipoprotein (MDA …