Resurgence of congenital syphilis: new strategies against an old foe

P Moseley, A Bamford, S Eisen, H Lyall… - The Lancet Infectious …, 2023 - thelancet.com
Congenital syphilis is a major global cause of fetal loss, stillbirth, neonatal death, and
congenital infection. In 2020, the global rate of congenital syphilis was 425 cases per 100 …

Treatment options for neonatal infections in the post-cefotaxime era

S Franco, D Rampersad, D Mesa… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Cefotaxime has been used for the management of neonatal infections since the
1990s for suspected meningitis and to mitigate gentamicin-associated renal injury. Its …

Securing the supply of benzathine penicillin: a global perspective on risks and mitigation strategies to prevent future shortages

F Seghers, MM Taylor, A Storey, J Dong… - International …, 2024 - academic.oup.com
Benzathine benzylpenicillin is a globally indispensable medicine. As a long-lasting
injectable penicillin, it serves as the primary treatment for syphilis, group A streptococcal …

Follow-up of infants with congenital syphilis during the penicillin shortage period

AFB Rocha, MAL Araújo, AKD Oliveira, LF Oliveira… - Jornal de …, 2023 - SciELO Brasil
Objective To analyze the follow-up, in specialized outpatient clinics, of infants reported with
congenital syphilis during the penicillin shortage. Method A cross-sectional study was …

Mortality in children under 5 years of age with congenital syphilis in Brazil: A nationwide cohort study

ES Paixao, AJF Ferreira, IO Dos Santos… - Plos …, 2023 - journals.plos.org
Background Congenital syphilis (CS) is a major and avoidable cause of neonatal death
worldwide. In this study, we aimed to estimate excess all-cause mortality in children under 5 …

Managing drug shortages in pediatric care

A Rosário, B Hankó, R Zelkó - Frontiers in Pharmacology, 2024 - frontiersin.org
The global impact of drug shortages on healthcare systems is a concerning issue that needs
urgent attention. These shortages not only jeopardize patient care, public health, and …

Managing Antibiotic Shortages in Inpatient Care—A Review of Recent Years in Comparison with the Hungarian Status

L Lőrinczy, B Turbucz, B Hankó, R Zelkó - Antibiotics, 2023 - mdpi.com
This study aimed to summarize the screened articles on antibiotic shortages, compare them
with the Hungarian Health Authority database, and identify the overlapping substances in …

Congenital Syphilis

A Dendi, H Sobrero, MM Castellano… - Principles of …, 2024 - Elsevier
The fetus and the newborn infant can get infected by Treponema pallidum, a bacterium from
the family Spirochaetaceae. A large number of new cases of congenital syphilis continue to …

Congenital Syphilis

SM Lawrence - Neonatology Questions and Controversies …, 2023 - books.google.com
• The incidence of syphilis in the United States has been increasing since 2012.• The two
leading causes of missed congenital syphilis prevention opportunities are the lack of …

An Alternative Treatment Option for Congenital Syphilis: A Case Series

M Shirolkar, R Verneker - Medical Journal of Dr. DY Patil …, 2024 - journals.lww.com
Newborn babies born to untreated syphilis-positive mothers need to be treated adequately
and timely to prevent and cure congenital syphilis. Penicillin is one of the most robust and …