The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Aim We tested the hypothesis that dapagliflozin may regress left ventricular hypertrophy
(LVH) in people with type 2 diabetes (T2D). Methods and results We randomly assigned 66 …

The metabolic syndrome (MetS) is defined as the concurrence of obesity-associated
cardiovascular risk factors including abdominal obesity, impaired glucose tolerance …

The combination of obesity and hypertension is associated with high morbidity and mortality
because it leads to cardiovascular and kidney disease. Potential mechanisms linking …

Obesity produces a variety of hemodynamic alterations that may cause changes in cardiac
morphology which predispose to left and right ventricular dysfunction. Various …

Obesity has reached epidemic proportions in the United States and worldwide. Considering
the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function …

Obesity-related cardiovascular disease in children is becoming more prevalent in
conjunction with the rise in childhood obesity. Children with obesity are predisposed to an …

There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …

The escalating prevalence of obesity has been linked to substantial increases in both
metabolic and cardiovascular disease. Nevertheless, the direct effects of obesity on …