[HTML][HTML] The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application
Eukaryotic cells produce extracellular vesicles (EVs) mediating intercellular communication.
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …
Recent updates on viral Oncogenesis: Available preventive and therapeutic entities
Human viral oncogenesis is a complex phenomenon and a major contributor to the global
cancer burden. Several recent findings revealed cellular and molecular pathways that …
cancer burden. Several recent findings revealed cellular and molecular pathways that …
Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)
S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …
[HTML][HTML] Decoding pathogenesis factors involved in the progression of ATLL or HAM/TSP after infection by HTLV-1 through a systems virology study
M Zarei Ghobadi, R Emamzadeh, M Teymoori-Rad… - Virology journal, 2021 - Springer
Abstract Background Human T-cell Leukemia Virus type-1 (HTLV-1) is a retrovirus that
causes two diseases including Adult T-cell Leukemia/Lymphoma (ATLL cancer) and HTLV-1 …
causes two diseases including Adult T-cell Leukemia/Lymphoma (ATLL cancer) and HTLV-1 …
[HTML][HTML] HTLV-1 reverse transcriptase homology model provides structural basis for sensitivity to existing nucleoside/nucleotide reverse transcriptase inhibitors
N Tardiota, N Jaberolansar, JA Lackenby, KJ Chappell… - Virology Journal, 2024 - Springer
The human T-lymphotropic virus type 1 (HTLV-1) infects millions of people globally and is
endemic to various resource-limited regions. Infections persist for life and are associated …
endemic to various resource-limited regions. Infections persist for life and are associated …
PD-1 and PD-L1 inhibitors foster the progression of adult T-cell Leukemia/Lymphoma
M Jalili-Nik, A Soltani, B Mashkani… - International …, 2021 - Elsevier
Immunotherapy through immune checkpoints blockade and its subsequent clinical
application has revolutionized the treatment of a spectrum of solid tumors. Blockade of …
application has revolutionized the treatment of a spectrum of solid tumors. Blockade of …
[HTML][HTML] HTLV-1 transmission and HIV pre-exposure prophylaxis: a scoping review
D Bradshaw, GP Taylor - Frontiers in Medicine, 2022 - frontiersin.org
HIV pre-exposure prophylaxis (HIV-PrEP) is effective in reducing the likelihood of HIV
acquisition in HIV-negative people at high risk of exposure. Guidelines recommend testing …
acquisition in HIV-negative people at high risk of exposure. Guidelines recommend testing …
Antiviral drug targets of single-stranded RNA viruses causing chronic human diseases
Ribonucleic acid (RNA) viruses associated with chronic diseases in humans are major
threats to public health causing high mortality globally. The high mutation rate of RNA …
threats to public health causing high mortality globally. The high mutation rate of RNA …
Transcriptional regulators of human oncoviruses: structural and functional implications for anticancer therapy
I Nečasová, M Stojaspal, E Motyčáková, T Brom… - NAR …, 2022 - academic.oup.com
Transcription is often the first biosynthetic event of viral infection. Viruses produce
preferentially viral transcriptional regulators (vTRs) essential for expressing viral genes and …
preferentially viral transcriptional regulators (vTRs) essential for expressing viral genes and …
[HTML][HTML] Human T-lymphotropic virus type 1 and antiretroviral therapy: practical considerations for pre-exposure and post-exposure prophylaxis, transmission …
JS O'Donnell, N Jaberolansar, KJ Chappell - The Lancet Microbe, 2024 - thelancet.com
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus associated with substantial risk
of secondary (often life-threatening) disease for the estimated 10 million to 20 million people …
of secondary (often life-threatening) disease for the estimated 10 million to 20 million people …