MUC16: molecular analysis and its functional implications in benign and malignant conditions

D Haridas, MP Ponnusamy, S Chugh… - The FASEB …, 2014 - Wiley Online Library
MUC16 is a high‐molecular‐weight glycoprotein that is expressed by the various epithelial
cell surfaces of the human body to protect the cell layer from a myriad of insults. It is the …

Tumor markers in the management of patients with ovarian cancer

MK Tuxen, G Sölétormos, P Dombernowsky - Cancer treatment reviews, 1995 - Elsevier
Epithelial ovarian cancer constitutes one-quarter of the gynecologic malignancies, but is the
leading cause of death among women with gynecologic cancer. In 60-70% of the women …

Comparison of serum human epididymis protein 4 with cancer antigen 125 as a tumor marker in patients with malignant and nonmalignant diseases

JM Escudero, JM Auge, X Filella, A Torne… - Clinical …, 2011 - academic.oup.com
BACKGROUND Human epididymis protein 4 (HE4), a precursor of human epididymis
protein, has been proposed as a tumor marker for ovarian cancer. We evaluated HE4 in …

Assessment of a combined panel of six serum tumor markers for lung cancer

R Molina, RM Marrades, JM Augé… - American journal of …, 2016 - atsjournals.org
Rationale: We have previously identified six serum tumor markers (TMs)(carcinoembryonic
antigen, carbohydrate antigen 15.3, squamous cell carcinoma–associated antigen …

[HTML][HTML] HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases

R Molina, JM Escudero, JM Augé, X Filella, L Foj… - Tumor Biology, 2011 - Springer
The aim of this study is to evaluate a new tumour marker, HE4, in comparison with CA 125
and the Risk of Ovarian Malignancy Algorithm (ROMA) in healthy women and in patients …

Usefulness of serum tumor markers, including progastrin-releasing peptide, in patients with lung cancer: correlation with histology

R Molina, JM Augé, X Bosch, JM Escudero, N Viñolas… - Tumor Biology, 2009 - karger.com
Background: Tumor markers have been extensively studied in lung cancer, reporting some
relationship to the histology, but their clinical utility is not clear. Methods: ProGRP, CEA …

Mucins CA 125, CA 19.9, CA 15.3 and TAG-72.3 as tumor markers in patients with lung cancer: comparison with CYFRA 21-1, CEA, SCC and NSE

R Molina, JM Auge, JM Escudero, R Marrades… - Tumor Biology, 2009 - karger.com
Tumor marker serum levels were prospectively studied in 289 patients with suspected, but
unconfirmed, lung cancer and in 513 patients with lung cancer [417 non-small cell lung …

Ascites: diagnosis and management

W Hou, AJ Sanyal - Medical Clinics, 2009 - medical.theclinics.com
Ascites is a common complication of cirrhosis. The development of ascites marks the onset
of worsened prognosis and increased mortality in patients with cirrhosis. Ascites also causes …

CA 125 secretion by peritoneal mesothelial cells.

AM Zeillemaker, HA Verbrugh… - Journal of clinical …, 1994 - jcp.bmj.com
AIMS--To investigate the secretion of the tumour marker CA 125 by cultured human
mesothelial cells; to determine if secretion of CA 125 could be observed by activating the …

[HTML][HTML] Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis

Y Koyama, P Wang, S Liang, K Iwaisako… - The Journal of …, 2017 - Am Soc Clin Investig
Cholestatic liver fibrosis is caused by obstruction of the biliary tract and is associated with
early activation of portal fibroblasts (PFs) that express Thy-1, fibulin 2, and the recently …