Recent advances in monoclonal antibody-based approaches in the management of bacterial sepsis
K Kharga, L Kumar, SKS Patel - Biomedicines, 2023 - mdpi.com
Sepsis is a life-threatening condition characterized by an uncontrolled inflammatory
response to an infectious agent and its antigens. Immune cell activation against the antigens …
response to an infectious agent and its antigens. Immune cell activation against the antigens …
Production of monoclonal antibodies for therapeutic purposes: A review
WP Alejandra, JPM Irene, GSF Antonio… - International …, 2023 - Elsevier
Monoclonal antibodies (mAbs) have been used in the development of immunotherapies that
target a variety of diseases, such as cancer, autoimmune diseases, and even viral infections; …
target a variety of diseases, such as cancer, autoimmune diseases, and even viral infections; …
Waning immunity and IgG4 responses following bivalent mRNA boosting
Messenger RNA (mRNA) vaccines were highly effective against the ancestral SARS-CoV-2
strain, but the efficacy of bivalent mRNA boosters against XBB variants was substantially …
strain, but the efficacy of bivalent mRNA boosters against XBB variants was substantially …
[HTML][HTML] Preexisting immunity restricts mucosal antibody recognition of SARS-CoV-2 and Fc profiles during breakthrough infections
Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination
is crucial to develop strategies for longer term immunity, especially against emerging viral …
is crucial to develop strategies for longer term immunity, especially against emerging viral …
[PDF][PDF] Systemic vasculitis: one year in review 2022
G La Rocca, G Del Frate, P Delvino… - Clin Exp …, 2022 - clinexprheumatol.org
Systemic vasculitis are rare heterogeneous disorders potentially involving any organ and
system with a relevant burden of mortality and comorbidity. As in the previous annual …
system with a relevant burden of mortality and comorbidity. As in the previous annual …
Pathophysiological effects of autoantibodies in autoimmune encephalitides
M Ryding, AW Mikkelsen, MS Nissen, AC Nilsson… - Cells, 2023 - mdpi.com
The heterogeneity of autoantibody targets in autoimmune encephalitides presents a
challenge for understanding cellular and humoral pathophysiology, and the development of …
challenge for understanding cellular and humoral pathophysiology, and the development of …
Serological and molecular characterization of hepatitis C virus-related cryoglobulinemic vasculitis in patients without cryoprecipitate
Prolonged B cells stimulation due to the Hepatitis C virus (HCV) can result in autoimmunity,
stigmatized by rising levels of cryoglobulins (CGs), the rheumatoid factor (RF), and free light …
stigmatized by rising levels of cryoglobulins (CGs), the rheumatoid factor (RF), and free light …
Collision induced unfolding enables the quantitation of Isomass biotherapeutics in complex biological matrices
BR Juliano, BT Ruotolo - Journal of the American Society for …, 2023 - ACS Publications
Quantitative mass spectrometry has been widely used to evaluate the concentrations of
molecules within a variety of biological matrices. Typically, such quantitative mass …
molecules within a variety of biological matrices. Typically, such quantitative mass …
Emerging Methods in Biosensing of Immunoglobin G—A Review
Human antibodies are produced due to the activation of immune system components upon
exposure to an external agent or antigen. Human antibody G, or immunoglobin G (IgG) …
exposure to an external agent or antigen. Human antibody G, or immunoglobin G (IgG) …
[HTML][HTML] Therapeutic plasma exchange versus FcRn inhibition in autoimmune disease
Therapeutic plasma exchange (TPE or PLEX) is used in a broad range of autoimmune
diseases, with the goal of removing autoantibodies from the circulation. A newer approach …
diseases, with the goal of removing autoantibodies from the circulation. A newer approach …