Abstract PROteolysis TArgeting Chimeras (PROTACs) technology is a new protein-
degradation strategy that has emerged in recent years. It uses bifunctional small molecules …

Breast cancer is the most frequently diagnosed cancer in women and ranks second among
causes for cancer related death in women. Evidence in literature has shown that the past …

The efficacy of current standard chemotherapy is suboptimal due to the poor solubility and
short half-lives of chemotherapeutic agents, as well as their high toxicity and lack of …

Breast cancer remains a worldwide public health dilemma and is currently the most common
tumour in the globe. Awareness of breast cancer, public attentiveness, and advancement in …

Abstract Ginger (Zingiber officinale Roscoe) has been used as a food, spice, supplement
and flavoring agent and in traditional medicines due to its beneficial characteristics such as …

Transcription factors (TFs) represent a major class of therapeutic targets for the treatment of
human diseases including cancer. Although the biological functions and even crystal …

G protein-coupled receptors (GPCRs) are the largest class of receptors in the human
genome and some of the most common drug targets. It is now well established that GPCRs …

The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …

Osteoporosis is an enormous and growing public health problem. Once considered an
inevitable consequence of ageing, it is now eminently preventable and treatable. Ironically …

Soy is a basic food ingredient of traditional Asian cuisine used for thousands of years. In
Western countries, soybeans have been introduced about a hundred years ago and recently …