To overcome cancer-associated immunosuppression, we prepared a dual-targeting vector
to deliver CpG oligodeoxynucleotides (ODN) to macrophages. The dual-targeting system …

Background The progression of prostate cancer to castration-resistant prostate cancer
(CRPC) is often a result of somatic alterations in the PI3K/Akt/mTOR (mammalian target of …

Simple Summary Prostate cancer presents a significant global public health burden. One of
its established risk factors is high fat diet. It has been proven that cholesterol levels in blood …

Dioscin has been known for its anti-cancer activity; however, its detailed molecular
mechanisms have not been studied so far. Herein, we evaluated the anti-cancer activity of …

Background Chemotherapeutic insensitivity remains a big challenge in prostate cancer
treatment. Recently, increasing evidence has indicated that KLF4 plays a key role in prostate …

OBJECTIVES: MicroRNAs (miRNAs) are the small non-coding regulatory RNA molecules
involved in gene regulation via base-pairing with complementary sequences in mRNAs. The …

Background: In recent decades, obesity has widely emerged as an important risk factor for
prostate cancer (PCa). Adipose tissue and PCa cells have been shown to orchestrate a …

MicroRNAs (miRNAs) are strongly implicated in various cancers, including prostate cancer.
Recently, microRNA-455-3p (miR-455-3p) has been shown to be aberrantly expressed in …

Intravenously administered radiolabeled peptides targeting somatostatin receptors are used
for the treatment of unresectable gastroenteropancreatic neuroendocrine tumors (GEP …

Simple Summary Obesity is involved in many aspects of prostate cancer progression as a
risk factor for prostate cancer, especially in the process of biochemical recurrence in the …