BACKGROUND Worldwide, placenta-related complications contribute to adverse pregnancy
outcomes, such as pre-eclampsia, fetal growth restriction and preterm birth, with implications …

Gestational diabetes mellitus (GDM) is a form of diabetes that is first diagnosed during
pregnancy in the absence of existing type 1 or type 2 diabetes. Early screening tools for …

Background Maternal overweight, obesity, and gestational diabetes (GD) have been
negatively associated with offspring development. Further knowledge regarding metabolic …

Introduction Placental fatty acid (FA) uptake and metabolism depend on maternal supply
which may be altered when women have a high pre-pregnancy body mass index (BMI) or …

Results: pBMI was significantly associated with 40 metabolites. Nonesterified fatty acids
(NEFA) showed a strong positive association with pBMI, with specificity for mono …

Abstract Background/Aims: Fetal metabolism may be changed by the exposure to maternal
factors, and the route to obesity may already set in utero. Cord blood metabolites might …

Inositols, a group of 6-carbon polyols, are highly bioactive molecules derived from diet and
endogenous synthesis. Inositols and their derivatives are involved in glucose and lipid …

Early identification of patients at risk of developing preeclampsia (PE) would allow providers
to tailor their prenatal management and adopt preventive strategies, such as low-dose …

Background: Over the last decades, research on early life risk factors for obesity and its
comorbidities in early life has gained attention within the field of developmental origins of …

Gestational diabetes (GDM) is one of the most common complications occurring during
pregnancy. Diagnosis is performed by oral glucose tolerance test, but harmonized testing …