Ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, was identified
as a distinct phenomenon and named a decade ago. Ferroptosis has been implicated in a …

In mammals, hundreds of proteins use iron in a multitude of cellular functions, including vital
processes such as mitochondrial respiration, gene regulation and DNA synthesis or repair …

Ferroptosis is an iron-dependent form of regulated cell death that is triggered by the toxic
build-up of lipid peroxides on cellular membranes. In recent years, ferroptosis has garnered …

Ferroptosis, a newly emerged form of regulated necrotic cell death, has been demonstrated
to play an important role in multiple diseases including cancer, neurodegeneration, and …

Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by
excessive lipid peroxidation and associated with a plethora of pathological conditions in the …

Iron dysregulation has been implicated in multiple neurodegenerative diseases, including
Parkinson's disease (PD). Iron-loaded microglia are frequently found in affected brain …

The hallmark of tumorigenesis is the successful circumvention of cell death regulation for
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …

The discovery of regulated cell death processes has enabled advances in cancer treatment.
In the past decade, ferroptosis, an iron-dependent form of regulated cell death driven by …

The research field of ferroptosis has seen exponential growth over the past few years, since
the term was coined in 2012. This unique modality of cell death, driven by iron-dependent …

Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …