[HTML][HTML] Advances in the role and mechanism of miRNA in inflammatory pain

X Zhang, L Zhu, X Wang, L Xia, Y Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Pain is a distressing experience associated with tissue damage or potential tissue damage,
and its occurrence is related to sensory, emotional, cognitive and social factors …

Research progress and challenges of TRPV1 channel modulators as a prospective therapy for diabetic neuropathic pain

C Liu, R Miao, F Raza, H Qian, X Tian - European Journal of Medicinal …, 2023 - Elsevier
Diabetic neuropathic pain (DNP) is a common, complex, and severe complication of
diabetes. It can lead to increased mortality, lower-limb amputations, and distressing …

Cannabidiol enhances the antinociceptive effects of morphine and attenuates opioid-induced tolerance in the chronic constriction injury model

CHA Jesus, MV Ferreira, AT Gasparin, ES Rosa… - Behavioural Brain …, 2022 - Elsevier
Neuropathic pain (NP) is a complex health problem that includes sensorial manifestations
such as evoked and ongoing pain. Cannabidiol (CBD) has shown potential in the treatment …

Cwc22-Mediated alternative splicing of Spp1 regulates nociception in inflammatory pain

Y Song, ZY Wang, J Luo, WC Han, XY Wang, C Yin… - Neuroscience, 2023 - Elsevier
Increasing evidence suggests that alternative splicing plays a critical role in pain, but its
underlying mechanism remains elusive. Herein, we employed complete Freund's adjuvant …

Downregulation of TRPM7, TRPM8, and TRPV1 channels modulate apoptotic parameters and neurodegenerative markers: Focus on neuronal differentiation and …

A Öz, Ö Çelik - Cell biology international, 2023 - Wiley Online Library
The transient receptor potential channel (TRP) channels are expressed in neuronal tissues
and involved in neurological diseases such as pain, epilepsy, neuronal apoptosis, and …

[HTML][HTML] Current insights and therapeutic strategies for targeting TRPV1 in neuropathic pain management

MM Rahman, YY Jo, YH Kim, CK Park - Life Sciences, 2024 - Elsevier
Neuropathic pain, a common symptom of several disorders, exerts a substantial
socioeconomic burden worldwide. Transient receptor potential vanilloid 1 (TRPV1), a non …

Bibliometric Analysis of Global Research on Transient Receptor Potential Vanilloid 1 in the Field of Pain

S Wang, W Wang, X Ye - Journal of Pain Research, 2023 - Taylor & Francis
Background Transient Receptor Potential Vanilloid 1 (TRPV1) is a heat-activated cation
channel modulated by inflammatory mediators, which is closely related to pain and serves …

Pharmacological agents targeting transient receptor potential (TRP) channels in neuropathic pain: Preclinical and clinical status

A Dangi, SS Sharma - European Journal of Pharmacology, 2024 - Elsevier
Abstract Neuropathic pain generally affects 7–10% population worldwide and an
estimated∼ 1 in every 20 individuals in western countries suffer and burden to society. The …

Curcumin and Resveratrol: Nutraceuticals with so Much Potential for Pseudoachondroplasia and Other ER-Stress Conditions

KL Posey - Biomolecules, 2024 - mdpi.com
Natural products with health benefits, nutraceuticals, have shown considerable promise in
many studies; however, this potential has yet to translate into widespread clinical use for any …

Evaluating the anti-neuropathic effects of naringin-loaded chitosan nanocarriers in a murine model of constriction injury

M Safari, S Fakhri, H Maleki… - Journal of Bioactive …, 2024 - journals.sagepub.com
Peripheral neuropathies are associated with various detrimental complications, leading to
life-debilitating disorders, including neuropathic pain. Hence, the current study aimed to …