COVID-19 in people with diabetes: understanding the reasons for worse outcomes

M Apicella, MC Campopiano, M Mantuano… - The lancet Diabetes & …, 2020 - thelancet.com
Since the initial COVID-19 outbreak in China, much attention has focused on people with
diabetes because of poor prognosis in those with the infection. Initial reports were mainly on …

ACE2 in the era of SARS-CoV-2: controversies and novel perspectives

F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …

有氧运动调控自发性高血压模型大鼠心脏重塑的机制

朱政, 付常喜, 马文超, 马刚, 彭朋 - 中国组织工程研究, 2022 - cjter.com
有氧运动调控自发性高血压模型大鼠心脏重塑的机制 Page 1 Chinese Journal of Tissue
Engineering Research|Vol 26|No.14|May 2022|2231 中国组织工程研究 Chinese Journal of …

COVID-19–Induced modifications in the tumor microenvironment: do they affect cancer reawakening and metastatic relapse?

F Francescangeli, ML De Angelis, M Baiocchi… - Frontiers in …, 2020 - frontiersin.org
Severe coronavirus disease 2019 (COVID-19) causes an uncontrolled activation of the
innate immune response, resulting in acute respiratory distress syndrome and systemic …

[HTML][HTML] Candesartan could ameliorate the COVID-19 cytokine storm

AG Elkahloun, JM Saavedra - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Abstract Background Angiotensin receptor blockers (ARBs) reducing inflammation and
protecting lung and brain function, could be of therapeutic efficacy in COVID-19 patients …

COVID-19, angiotensin receptor blockers, and the brain

JM Saavedra - Cellular and Molecular Neurobiology, 2020 - Springer
The abundant scientific information on the COVID-19 pandemic we receive through
academic publications and correspondence, as well as through social media, is sometimes …

Catalpol Attenuates Pulmonary Fibrosis by Inhibiting Ang II/AT1 and TGF-β/Smad-Mediated Epithelial Mesenchymal Transition

Q Yu, D Zhu, Y Zou, K Wang, P Rao, Y Shen - Frontiers in Medicine, 2022 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is a progressive and devastating chronic
lung condition affecting over 3 million people worldwide with a high mortality rate and there …

Insights to potential antihypertensive activity of berry fruits

M Yousefi, M Shadnoush, N Khorshidian… - Phytotherapy …, 2021 - Wiley Online Library
Hypertension is one of the main risk factors for cardiovascular disease and causes
widespread morbidity and mortality worldwide. Although several antihypertensive drugs …

The emerging role of angiotensinogen in cardiovascular diseases

Y Xu, J Rong, Z Zhang - Journal of Cellular Physiology, 2021 - Wiley Online Library
Angiotensinogen (AGT) is the unique precursor of all angiotensin peptides. Many of the
basic understandings of AGT in cardiovascular diseases have come from research efforts to …

Losartan enhances cognitive and structural neuroplasticity impairments in spontaneously hypertensive rats

H Coatl-Cuaya, H Tendilla-Beltrán… - Journal of Chemical …, 2022 - Elsevier
Hypertension is a risk factor for vascular dementia, which is the second most prevalent type
of dementia, just behind Alzheimer's disease. This highlights the brain vulnerability due to …