Background The relationship between surgery and anesthetic-induced immunosuppression
and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the …

Morphine is an analgesic widely used to alleviate cancer pain. In addition, the perioperative
management of pain in cancer surgery patients most often includes opioids. However, there …

Postoperative nausea and vomiting (PONV) and pain are two of the major concerns for
patients presenting for surgery. The causes of PONV are multifactorial and can largely be …

Abstract EDITOR'S PERSPECTIVE What We Know about This Topic IV anesthesia may
impair anticancer immunity less than volatile anesthesia and therefore reduce recurrence …

Recent epidemiologic studies implying differences in cancer recurrence based on
anesthetic regimens raise the possibility that the mu opioid receptor (MOR) can influence …

Background Recent epidemiologic studies suggesting that there were differences in cancer
recurrence contingent on anesthetic regimens have raised the possibility that μ-opioid …

Background We and others have previously demonstrated that the μ-opioid receptor (MOR)
is overexpressed in several human malignancies. There is a seven-fold increase in MOR in …

THERE has been increasing interest in the role of anes-thetic drugs and opioids in cancer
recurrence and metastasis. Epidemiologic studies in this area have suggested that patients …

Cancer, currently the leading cause of death in the population aged less than 85 years,
poses a significant global disease burden and is anticipated to continue to increase in …

Morphine is considered the “gold standard” for relieving pain and is currently one of the most
effective drugs available clinically for the management of severe pain associated with …